A Canadian-led study involving researchers from 41 countries has demonstrated in a study of acute coronary syndromes (ACS) that a new anti-thrombotic therapy is safer and as effective as the traditional therapy used in preventing heart attacks, death and ischemia in people with serious heart conditions.
The OASIS-5/MICHELANGELO study, presented today at the European Society of Cardiology meeting in Stockholm, Sweden, showed that fondaparinux, a new anti-thrombotic therapy, was as effective as enoxaparin in preventing heart attacks, death and ischemia (reduction in blood supply to the tissues) at nine days after an event but demonstrated a dramatic reduction in major bleeding. The study indicated patients had a lower mortality rate at the one-month mark after an acute coronary event. This finding remained consistent throughout the following six months of follow-up.
These favourable effects resulted in a clear net benefit in favour of fondaparinux throughout the study, said Dr. Salim Yusuf, principal investigator and chair of the international study.
Gina Dellios | EurekAlert!
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