Rats fed a high fat diet were less sensitive to a hormonal stop eating signal than rats on a low fat diet when they were given access to a high calorie, high fat snack that the animals find yummy.
Dr. Mihai Covasa, assistant professor of nutritional sciences and a member of the Penn State Neuroscience Institute, led the study. He says, "When we gave the rats doses of a stop eating hormone, the rats on the low fat diet significantly suppressed their intake of the snack but not the rats on the high fat diet."
Covasa adds, "These results suggest that a long-term, high-fat diet may actually promote short-term overconsumption of highly palatable foods high in dietary fat by reducing sensitivity to at least one important feedback signal which would ordinarily limit eating."
Barbara Hale | EurekAlert!
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