Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


’Good’ bacteria helps ease pain of colitis


A mixture of bacteria developed in part by University of Alberta researchers has been proven highly effective in treating people suffering from ulcerative colitis.

The findings, published in the July, 2005 issue of American Journal of Gastroenterology showed that the majority of patients taking a probiotic mixture of 8 bacteria (VSL#3) for 6 weeks improved their ulcerative colitis. Probiotics are preparations of living microbial cells that, when ingested, are thought to positively influence the composition of microbes in the gut and improve the health of the intestine.

While "bad" bacteria have been flagged as potential culprits in the cause of inflammatory diseases of the bowel, in this case, the ingestion of supplemental "good" bacteria (probiotics) to the intestine proved beneficial in treating ulcerative colitis, said Dr. Richard Fedorak, a professor of gastroenterology at the University of Alberta. The joint study included researchers from the University of Bologna in Italy and the University of North Carolina.

In this open label clinical trial, 86 per cent of those treated with probiotic bacteria mixture VSL#3 experienced relief of their mild to moderate ulcerative colitis. The mixture of eight lactic acid bacterial species is believed to be effective by mechanisms that include (1) reducing the number of "bad" bacteria, (2) reducing the amount of inflammation (3) increasing the mucus layer in the gut, and (4) increasing the amount of anti-inflammatory molecules in the intestine.

Ulcerative colitis is an inflammatory bowel disease that affects the large intestine (colon) and causes acute bloody diarrhea, sever stomach pain, urgency, anemia and fatigue. In its most severe form, ulcerative colitis that does not respond to medical treatment will require surgical removal of the colon.

The VSL#3 was administered over a six-week period to 30 patients who ranged in age from 18 to 65. Remission of the colitis was achieved in 63 per cent of the patients, while another 23 per cent responded with improvement in their symptoms and with healing of the colon’s lining. There were no adverse effects to the medication.

The VSL#3 can be considered an important potential treatment for those patients who don’t respond to conventional therapy such as mesalamine or 5ASA, Dr. Fedorak said.

Bev Betkowski | EurekAlert!
Further information:

More articles from Studies and Analyses:

nachricht Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung

nachricht High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Oasis of life in the ice-covered central Arctic

24.10.2016 | Earth Sciences

‘Farming’ bacteria to boost growth in the oceans

24.10.2016 | Life Sciences

Light-driven atomic rotations excite magnetic waves

24.10.2016 | Physics and Astronomy

More VideoLinks >>>