Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Recent use of antibiotics doubles your chances of being resistant

19.07.2005


New study shows that a prescription of antibiotics taken within the previous two months doubles the chances of patients carrying antibiotic resistant bacteria.



A new study has shown that a prescription of antibiotics taken within the previous two months doubles the chances of patients carrying antibiotic resistant bacteria. The same effect was not seen in patients who had had antibiotics prescribed within the previous 12 months.

While information from large data sets suggest that high levels of antibiotic use is related to antibiotic resistance, this is the first time that the risk to the individual has been assessed. The study looked at whether GP prescribing of antibiotics increases an individual’s risk of developing antibiotic resistance.


GPs are responsible for 80% of all antibiotics prescribed in the United Kingdom, despite evidence of limited or marginal effectiveness for the most common reason to prescribe, namely respiratory tract infections such as sore throats, coughs and earache. This could be partly due to patients’ expectations of being treated with antibiotics.

Dr Alastair Hay, from Bristol University who is also a GP in the city said: "Although GP’s are aware of the problem in the population as a whole, when deciding whether or not to prescribe antibiotics for an individual they may consider the risk as being minimal."

Resistance was tested in organisms from urine samples submitted by 3,000 adults without urinary symptoms registered with 12 GP practices in the Bristol and Gloucester areas. Hay and colleagues from across the South West found information on bacterial resistance and antibiotic consumption in 618 patients from their primary care medical records regarding the number, type, strength and duration of antibiotic courses prescribed in the 12 months prior to urine sample submission.

The urinary E. coli bacteria found in low concentrations were defined as resistant if they demonstrated resistance to the antibiotic amoxicillin or the antibiotic trimethoprim, or both antibiotics.

The results showed that antibiotics prescribed in the 12 months prior to obtaining the urine sample did not influence the resistance of organisms – presumably because the time period in question is too long. However, the more recent use of antibiotics – within 2 months – led to a near doubling of the likelihood of resistance.

The team also found that over a 12 month period prior to sampling, each additional tablet of trimethoprim (200mg) prescribed increased the chances of developing resistance. In addition, the degree of resistance to amoxicillin was greater in patients prescribed any penicillin antibiotic in the 12 months prior to urine sampling. Funded by the British Society for Antimicrobial Chemotherapy, the results of this work are published in the Journal of Antimicrobial Chemotherapy this month [July 2005]

This is the first time the risk to individuals being prescribed antibiotics by their GP has been measured. This research should be repeated but in the meantime both patients and GP’s should take account of this information when deciding whether to prescribe and consume antibiotics.

Cherry Lewis | EurekAlert!
Further information:
http://www.bristol.ac.uk

More articles from Studies and Analyses:

nachricht Real-time feedback helps save energy and water
08.02.2017 | Otto-Friedrich-Universität Bamberg

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

From rocks in Colorado, evidence of a 'chaotic solar system'

23.02.2017 | Physics and Astronomy

'Quartz' crystals at the Earth's core power its magnetic field

23.02.2017 | Earth Sciences

Antimicrobial substances identified in Komodo dragon blood

23.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>