Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Recent use of antibiotics doubles your chances of being resistant

19.07.2005


New study shows that a prescription of antibiotics taken within the previous two months doubles the chances of patients carrying antibiotic resistant bacteria.



A new study has shown that a prescription of antibiotics taken within the previous two months doubles the chances of patients carrying antibiotic resistant bacteria. The same effect was not seen in patients who had had antibiotics prescribed within the previous 12 months.

While information from large data sets suggest that high levels of antibiotic use is related to antibiotic resistance, this is the first time that the risk to the individual has been assessed. The study looked at whether GP prescribing of antibiotics increases an individual’s risk of developing antibiotic resistance.


GPs are responsible for 80% of all antibiotics prescribed in the United Kingdom, despite evidence of limited or marginal effectiveness for the most common reason to prescribe, namely respiratory tract infections such as sore throats, coughs and earache. This could be partly due to patients’ expectations of being treated with antibiotics.

Dr Alastair Hay, from Bristol University who is also a GP in the city said: "Although GP’s are aware of the problem in the population as a whole, when deciding whether or not to prescribe antibiotics for an individual they may consider the risk as being minimal."

Resistance was tested in organisms from urine samples submitted by 3,000 adults without urinary symptoms registered with 12 GP practices in the Bristol and Gloucester areas. Hay and colleagues from across the South West found information on bacterial resistance and antibiotic consumption in 618 patients from their primary care medical records regarding the number, type, strength and duration of antibiotic courses prescribed in the 12 months prior to urine sample submission.

The urinary E. coli bacteria found in low concentrations were defined as resistant if they demonstrated resistance to the antibiotic amoxicillin or the antibiotic trimethoprim, or both antibiotics.

The results showed that antibiotics prescribed in the 12 months prior to obtaining the urine sample did not influence the resistance of organisms – presumably because the time period in question is too long. However, the more recent use of antibiotics – within 2 months – led to a near doubling of the likelihood of resistance.

The team also found that over a 12 month period prior to sampling, each additional tablet of trimethoprim (200mg) prescribed increased the chances of developing resistance. In addition, the degree of resistance to amoxicillin was greater in patients prescribed any penicillin antibiotic in the 12 months prior to urine sampling. Funded by the British Society for Antimicrobial Chemotherapy, the results of this work are published in the Journal of Antimicrobial Chemotherapy this month [July 2005]

This is the first time the risk to individuals being prescribed antibiotics by their GP has been measured. This research should be repeated but in the meantime both patients and GP’s should take account of this information when deciding whether to prescribe and consume antibiotics.

Cherry Lewis | EurekAlert!
Further information:
http://www.bristol.ac.uk

More articles from Studies and Analyses:

nachricht Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Researchers release the brakes on the immune system

18.10.2017 | Health and Medicine

Separating methane and CO2 will become more efficient

18.10.2017 | Life Sciences

Ocean atmosphere rife with microbes

17.10.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>