Study raises hope of treating aggressive vascular malformations with anti-angiogenesis drugs
Vascular anomalies – birthmarks caused by abnormal development of arteries, capillaries, veins or lymph vessels – can sometimes begin to progress, requiring aggressive treatment to save the child’s health or vision. Research at Children’s Hospital Boston now suggests that urine testing can help monitor these anomalies and predict those about to become a serious threat. The findings, published in the July Pediatrics, also raise the possibility of new drug treatments for aggressive cases, particularly for hard-to-treat vascular malformations.
Vascular anomalies include both vascular malformations and vascular tumors (most commonly hemangiomas). Hemangiomas, found in about 10% of infants, occur when the cells lining blood vessels multiply abnormally, forming clusters of vessels. Hemangiomas grow rapidly in the first year of life, then usually shrink and disappear. But some grow quite large, causing obstruction, ulceration and other problems. Vascular malformations occur during fetal development and include lymphatic, venous, arteriovenous and capillary malformations. They usually grow in proportion to the child, but sometimes progress during adolescence or pregnancy, or after surgery or trauma, in rare instances becoming fatal. There are currently no effective drug treatments.
Elizabeth Andrews | EurekAlert!
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Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
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An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
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A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
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