Few front-line medications exist for treating hospitalized patients with acute decompensated heart failure, a stage of heart failure marked by heightened severity and often-lengthy hospital stays with frequent readmissions. Now, a study suggests the list of preferred drugs for treating the disease might be even shorter.
In a study released today (7/5) in the Journal of the American College of Cardiology, researchers found that two particular drugs were associated with substantially lower in-hospital mortality than two other drugs that also are commonly used for treating patients with acute decompensated heart failure (ADHF).
The retrospective study draws from a multi-institutional registry of 65,180 patients with ADHF. In comparisons of patients treated intravenously with nitroglycerin, nesiritide, dobutamine or milrinone, there was a lower in-hospital mortality rate for patients administered nitroglycerin or nesiritide than the drugs dobutamine or milrinone.
David Crawford | EurekAlert!
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