Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Poly/mono balance important to cholesterol-lowering diet

04.07.2005


In the search for the best fats for a heart healthy diet, trans- and saturated fats have long been recognized as undesirable and those that contain polyunsaturated fatty acids (PUFAs) and mono-unsaturated fatty acids (MUFAs) are preferred -- with no clear benefit demonstrated for higher levels of either the PUFAs or the MUFAs within recommended limits.



Now, a Penn State study provides evidence that the optimum dietary fat isn’t one that contains either more PUFAs or more MUFAs, but one that contains a proper balance of both to control cardiovascular risk factors.

In the Penn State study, detailed in the current issue of the Journal of the American Dietetic Association, two heart healthy oils, a new PUFA-rich sunflower oil (NuSun) and the more MUFA-rich olive oil, were compared in a diet designed to lower blood cholesterol levels.


Dr. Penny Kris Etherton, distinguished professor of nutrition who directed the study, says, "We expected the PUFAs, which are higher in the sunflower oil than the olive oil, to produce a greater reduction in total and LDL cholesterol levels in the study participants -- and they did. The surprise was the fact that the olive oil diet, which is also low in saturated fat, did not lower cholesterol levels compared with the average American diet. Also surprising was that the greater percentage of PUFAs in the NuSun sunflower oil diet did not increase LDL oxidation products that are risk factors for atherosclerosis."

The results are described in the paper, "Balance of Unsaturated Fatty Acids is Important to Cholesterol-Lowering Diet: Comparison of Mid-Oleic Sunflower Oil and Olive Oil on Cardiovascular Disease Risk Factors." The authors are Dr. Amy E. Binkoski, former Penn State doctoral student, Dr. Penny M. Kris-Etherton, distinguished professor of nutritional sciences, Dr. Thomas W. Wilson, assistant professor, University of Massachusetts Lowell, Margaret L. Mountain, dietitian, University of Pittsburgh Medical Center, and Dr. Robert J. Nicolosi, professor and director of the Center for Health and Disease Research, University of Massachusetts Lowell.

The researchers recruited 31 healthy men and women, ages 25 to 64, who had moderately elevated LDL cholesterol. The women’s LDL cholesterol was in the 140 to 188 range and the men’s was between 129 and 177.

The participants each ate three different diets: an olive oil-based diet, a NuSun sunflower oil-based diet or an average American diet. The two oil-based diets limited fat to 30 percent of calories and the average American diet had 34 percent fat calories. The volunteers ate each diet for four weeks, took a two-week break when they ate their usual diet and then moved on to the next diet. Blood samples were taken at the end of each diet period.

Analysis of the participants’ blood samples showed that the NuSun sunflower oil diet significantly reduced total and LDL cholesterol levels compared with the average American diet. No significant differences were observed between the olive oil diet and the average American diet.

The ratios of total cholesterol to HDL cholesterol and LDL to HDL cholesterol were not significantly different among the three diets. Triglyceride levels also were similar among all three diets.

Some previous studies have shown a greater production of oxidation products following consumption of a high PUFA diet compared with a high MUFA diet. However, in this study, while the NuSun sunflower diet did not have a beneficial effect on LDL oxidation, there were no adverse effects despite the increase in PUFAs.

Kris-Etherton says, "Within the context of a moderate fat diet, it is becoming clear that a mixture of unsaturated fatty acids provides the greatest health benefits."

Barbara Hale | EurekAlert!
Further information:
http://www.psu.edu

More articles from Studies and Analyses:

nachricht Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT

nachricht Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>