Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Herbal medicine may alter cell response to cancer therapeutic agents

27.04.2005


Black cohosh, an herb widely used by breast cancer patients to alleviate hot flashes and other menopausal symptoms, may alter the way that cells respond to drugs commonly used to treat breast cancer, according to a Yale School of Medicine study in Breast Cancer Research and Treatment.



Recent studies have shown that many patients receiving cancer therapy are also self-medicating with complementary and alternative medicines, often without telling their physicians, said the lead researcher, Sara Rockwell, professor of Therapeutic Radiology and Pharmacology at Yale School of Medicine. "Over 30 insurers now cover at least one alternative therapy, "she said. "Out-of-pocket spending for complementary and alternative medicines was recently estimated to be $27 billion per year, similar to the out-of-pocket costs for all physician services."

She said the herb is being widely used by and recommended to breast cancer patients who are experiencing menopausal symptoms due to removal from hormone replacement therapy or to the effects of their therapy.


In this study Rockwell and her team used a widely studied mouse breast cancer cell line to see whether commercially available extracts of black cohosh altered the response of cancer cells to radiation and to four drugs commonly used in cancer therapy.

Rockwell said the black cohosh increased cell killing by two of the drugs, decreased the effectiveness of one drug, and did not alter the effects of radiation or a fourth drug. Why each agent responded differently needs to be studied further, she said, but enough is known about the herb’s effects on cancer cells to caution patients about using and other over the counter agents without consulting their physicians.

"Our studies caution that black cohosh should not be considered to be a harmless herb that is inconsequential to the health of cancer patients or to the outcome of conventional cancer therapy," Rockwell said.

Jacqueline Weaver | EurekAlert!
Further information:
http://www.yale.edu

More articles from Studies and Analyses:

nachricht Obstructing the ‘inner eye’
07.07.2017 | Friedrich-Schiller-Universität Jena

nachricht Drone vs. truck deliveries: Which create less carbon pollution?
31.05.2017 | University of Washington

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: 3-D scanning with water

3-D shape acquisition using water displacement as the shape sensor for the reconstruction of complex objects

A global team of computer scientists and engineers have developed an innovative technique that more completely reconstructs challenging 3D objects. An ancient...

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Closing the Sustainability Circle: Protection of Food with Biobased Materials

21.07.2017 | Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

 
Latest News

Ultrathin device harvests electricity from human motion

24.07.2017 | Power and Electrical Engineering

Scientists announce the quest for high-index materials

24.07.2017 | Materials Sciences

ADIR Project: Lasers Recover Valuable Materials

24.07.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>