A new study by 64 renowned scientists may bring us one step closer to personalized medical treatment--that is, medical treatment tailored to each persons unique genetic make-up and medical condition. The study shows researchers how to get more consistent and reliable results when using a technology called microarrays or gene chips. Microarrays allow scientists to see how differences in gene expression are linked to specific diseases. Improving and standardizing microarray experiments will also allow earlier detection of diseases like cancer.
"The microarray is fairly new so, right now, researchers are using a lot of different methods and protocols in microarray experiments. That makes it hard for researchers to compare their results to results from other labs," said Kenneth Olden, Ph.D., Director of the National Institute of Environmental Health Sciences (NIEHS). "When scientists start using the same methods, equipment and reagents, data can be compared across the entire field of medicine and scientific advances will come more quickly."
The study, conducted by the Toxicogenomics Research Consortium, which is funded by the National Institute of Environmental Health Sciences, part of the National Institutes of Health, was initiated in 2001 to asses what causes variation in gene expression experiments within and between labs, as well as within and between microarray platforms. The TRC is a consortium of 7 research centers including: NIEHS Microarray Group of the National Center for Toxicogenomics, Duke University, Fred Hutchinson Cancer Research Center/University of Washington, Massachusetts Institute of Technology, Oregon Health and Sciences University, and University of North Carolina at Chapel Hill. Icoria Inc. was also a research partner. The paper appears in the May issue of Nature Methods.
Robin Mackar | EurekAlert!
WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf
First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
23.05.2018 | Life Sciences
23.05.2018 | Life Sciences
23.05.2018 | Physics and Astronomy