Some adults with mild persistent asthma may be able to adequately control their asthma by taking corticosteroids only when needed, instead of taking anti-inflammatory medication daily, according to new results from the Improving Asthma Control Trial (IMPACT). Conducted by the National Heart, Lung, and Blood Institutes (NHLBI) Asthma Clinical Research Network, the one-year, multi-center study found that participants who were treated with corticosteroids intermittently based on symptoms had about the same rate of severe exacerbations and of asthma-related lung function decline as those treated with the standard recommendation of daily long-term control medication.
Asthma is considered mild and persistent when individuals have acute symptoms such as wheezing, coughing, or chest tightness more than twice a week, but not daily, or they have night-time awakenings due to asthma more than two nights a month. The researchers caution that the new findings might not apply to people who have recently developed asthma. In addition, they do not apply to patients with more frequent symptoms or more severe asthma. The results are published in the April 14 issue of the New England Journal of Medicine.
"This study provides evidence of another possible way to treat adults with long-standing mild persistent asthma," stated Elizabeth G. Nabel, MD, director of the NHLBI, part of the National Institutes of Health. "If additional research confirms these findings, then some of these patients may be able to safely treat their asthma with intermittent medication and avoid the added expense and inconvenience of daily therapy. As for all asthma patients, however, individuals should work closely with their healthcare providers to develop and follow the treatment plan that suits them best."
The data coordinating center is at Penn State College of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.
The medications for IMPACT were donated by Astra-Zeneca Pharmaceuticals, headquartered in Wayne, Pennsylvania.
NHLBI Communications Office | EurekAlert!
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
23.08.2017 | Materials Sciences
23.08.2017 | Automotive Engineering
23.08.2017 | Life Sciences