Why does extra fat around the waist increase the risk of heart disease? A new study by Wake Forest University Baptist Medical Center researchers and colleagues suggests that inflammation may be the key.
"It is well known that obesity affects nearly one-third of adults in the United States and is closely linked with heart disease," said Tongjian You, Ph.D., instructor in geriatric medicine at Wake Forest Baptist and lead author. "While we dont fully understand the link between obesity and heart disease, our study suggests that inflammatory proteins produced by fat itself may play a role."
The study, to be published in the April issue of the American Journal of Physiology – Endocrinology and Metabolism, evaluated whether inflammatory proteins produced by fat are linked to risk factors for heart disease, including high blood pressure, high cholesterol and how the body responds to insulin. The research is based on a new idea in medicine – that fat is an "organ" that produces proteins and hormones that affect metabolism and health.
Karen Richardson | EurekAlert!
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