Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cornea transplants can be improved

14.03.2005


UHC study indicates need for new standards and training



Improving the training and standardizing the procedures used by the nation’s eye banks to assess corneal cells may help to select corneas with optimal health for transplantation, according to new study led by Jonathan H. Lass, MD, principal investigator of the study and chairman of the Department of Ophthalmology at University Hospitals of Cleveland and Case Western Reserve University School of Medicine.

This study is reported in the current (March) issue of Ophthalmology, the journal of the American Academy of Ophthalmology. The National Eye Institute and the Eye Bank Association of America funded this research.


The study, which is part of a larger Cornea Donor Study of 1,101 patients, was designed to evaluate the quality of the microscope images of the donor cornea and the number of donor cornea’s endothelial cells because those parameters may help to determine the long-term (at least ten years) survival of a transplanted cornea. (Endothelial cells form the back cell layer of the cornea and keep the cornea clear.)

When researchers measured the image quality and density of endothelial cells in the cornea, they were performing the same type of assessment that eye banks perform to ascertain whether a cornea is healthy enough for a transplant.

"Our results found that, over all, the current system for assessing quality and density of cells is good in the nation’s eye banks," Dr. Lass says. "But there is room for improvement in some eye banks’ assessment procedures, both in terms of enhancing image quality of the microscope image of the corneal cells and improving the accuracy of counting cells, parameters used to assess the health of a cornea."

More than 35,000 corneal transplants are performed annually in the United States, most of them on patients who undergo a corneal transplant because they have swelling due to cataract surgery or they have Fuchs’ Dystrophy, a condition in which the endothelial cells deteriorate.

Eye banks play a crucial role in cornea transplantation. According to the Eye Bank Association of America, eye banks supplied the corneal tissue for 32,144 transplants in 2003.

"Often, the eye bank cell counts were off by more than 10 percent," Dr. Lass says. "We believe these data will trigger the development of new methods, improved training and universal standards to ensure that healthier corneas are being transplanted."

Eric Sandstrom | EurekAlert!
Further information:
http://www.uhhs.com

More articles from Studies and Analyses:

nachricht Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT

nachricht Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>