Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cornea transplants can be improved

14.03.2005


UHC study indicates need for new standards and training



Improving the training and standardizing the procedures used by the nation’s eye banks to assess corneal cells may help to select corneas with optimal health for transplantation, according to new study led by Jonathan H. Lass, MD, principal investigator of the study and chairman of the Department of Ophthalmology at University Hospitals of Cleveland and Case Western Reserve University School of Medicine.

This study is reported in the current (March) issue of Ophthalmology, the journal of the American Academy of Ophthalmology. The National Eye Institute and the Eye Bank Association of America funded this research.


The study, which is part of a larger Cornea Donor Study of 1,101 patients, was designed to evaluate the quality of the microscope images of the donor cornea and the number of donor cornea’s endothelial cells because those parameters may help to determine the long-term (at least ten years) survival of a transplanted cornea. (Endothelial cells form the back cell layer of the cornea and keep the cornea clear.)

When researchers measured the image quality and density of endothelial cells in the cornea, they were performing the same type of assessment that eye banks perform to ascertain whether a cornea is healthy enough for a transplant.

"Our results found that, over all, the current system for assessing quality and density of cells is good in the nation’s eye banks," Dr. Lass says. "But there is room for improvement in some eye banks’ assessment procedures, both in terms of enhancing image quality of the microscope image of the corneal cells and improving the accuracy of counting cells, parameters used to assess the health of a cornea."

More than 35,000 corneal transplants are performed annually in the United States, most of them on patients who undergo a corneal transplant because they have swelling due to cataract surgery or they have Fuchs’ Dystrophy, a condition in which the endothelial cells deteriorate.

Eye banks play a crucial role in cornea transplantation. According to the Eye Bank Association of America, eye banks supplied the corneal tissue for 32,144 transplants in 2003.

"Often, the eye bank cell counts were off by more than 10 percent," Dr. Lass says. "We believe these data will trigger the development of new methods, improved training and universal standards to ensure that healthier corneas are being transplanted."

Eric Sandstrom | EurekAlert!
Further information:
http://www.uhhs.com

More articles from Studies and Analyses:

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

nachricht First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Powerful IT security for the car of the future – research alliance develops new approaches

The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.

Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

In focus: Climate adapted plants

25.05.2018 | Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

 
Latest News

In focus: Climate adapted plants

25.05.2018 | Event News

Flow probes from the 3D printer

25.05.2018 | Machine Engineering

Less is more? Gene switch for healthy aging found

25.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>