Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

MRI Proves Useful in Assessment of Suspected Breast Cancer Patients

07.03.2005


If a mammogram or sonogram suggests that a woman has breast cancer, an MRI should be done to help determine whether there actually is a cancer and if so, what are the woman’s best treatment options, a new study shows. The study, done in a large community hospital, found that MR images, which were acquired and analyzed in a specific way, can help identify if a lesion is benign or malignant and can show cancers that would otherwise be missed.



“This is the first time a prospective study has been done that shows that MRI (using a contrast agent) can work in a real life community setting - the setting in which most breast cancer patients are diagnosed and treated,” said Jonathan I. Wiener, MD, lead author of the study. The study included 65 patients who had “highly suspicious” findings on mammography or sonography and were believed to be candidates for breast conserving treatment. Nineteen of the patients did not have a suspicious lesion on MRI, and when these women were biopsied, it turned out they did not have cancer, said Dr. Wiener. Many of those patients could have avoided having a biopsy at all, he said.

In addition, MRI detected 23 additional cancers in the 44 patients that actually had a breast cancer (either in the same breast as the primary cancer and or in the opposite breast) that were not detected on mammography or sonography. Because of the additional information provided by MRI, and subseqently confirmed by pathological analysis of the biopsy specimens, it was recommended that eight women have a mastectomy rather than breast conservation treatment. “About 15% of breast cancer patients have a recurrence of their disease. We don’t know precisely why cancer returns in previously thought to be adequately treated breast cancer patients. One of the reasons could be that many of the cancers may be missed initially with only a conventional work up with mammography and ultrasound. The addition of MRI will improve the accuracy of breast cancer diagnosis,” Dr. Wiener said.


“Breast MRI using contrast agents has been around for about 15 years,” said Dr. Wiener. “Breast MRI isn’t widely used because there are concerns that it detects too many lesions that are not cancer, thereby causing too many women to undergo unnecessary biopsies. However we used a special computer program (computer assisted diagnosis), which helped us analyze the MRI images, looking at both morphology and kinetics. Morphology looks at the shape of the lesion, while kinetics looks at how quickly the contrast agent lights up the lesion then fades away. If the lesion is bright then washes out quickly, it usually indicates cancer,” he said. “By analyzing MRI using these and other factors, as well as carefully reviewing the mammograms and sonograms, we were able to more accurately answer the vital questions: does the patient have breast cancer and how extensive is the disease?” said Dr. Wiener.

The study appears in the March 2005 issue of the American Journal of Roentgenology.

Jason Ocker | EurekAlert!
Further information:
http://www.arrs.org

More articles from Studies and Analyses:

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Tracking movement of immune cells identifies key first steps in inflammatory arthritis

23.01.2017 | Health and Medicine

Electrocatalysis can advance green transition

23.01.2017 | Physics and Astronomy

New technology for mass-production of complex molded composite components

23.01.2017 | Process Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>