Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

MRI Proves Useful in Assessment of Suspected Breast Cancer Patients

07.03.2005


If a mammogram or sonogram suggests that a woman has breast cancer, an MRI should be done to help determine whether there actually is a cancer and if so, what are the woman’s best treatment options, a new study shows. The study, done in a large community hospital, found that MR images, which were acquired and analyzed in a specific way, can help identify if a lesion is benign or malignant and can show cancers that would otherwise be missed.



“This is the first time a prospective study has been done that shows that MRI (using a contrast agent) can work in a real life community setting - the setting in which most breast cancer patients are diagnosed and treated,” said Jonathan I. Wiener, MD, lead author of the study. The study included 65 patients who had “highly suspicious” findings on mammography or sonography and were believed to be candidates for breast conserving treatment. Nineteen of the patients did not have a suspicious lesion on MRI, and when these women were biopsied, it turned out they did not have cancer, said Dr. Wiener. Many of those patients could have avoided having a biopsy at all, he said.

In addition, MRI detected 23 additional cancers in the 44 patients that actually had a breast cancer (either in the same breast as the primary cancer and or in the opposite breast) that were not detected on mammography or sonography. Because of the additional information provided by MRI, and subseqently confirmed by pathological analysis of the biopsy specimens, it was recommended that eight women have a mastectomy rather than breast conservation treatment. “About 15% of breast cancer patients have a recurrence of their disease. We don’t know precisely why cancer returns in previously thought to be adequately treated breast cancer patients. One of the reasons could be that many of the cancers may be missed initially with only a conventional work up with mammography and ultrasound. The addition of MRI will improve the accuracy of breast cancer diagnosis,” Dr. Wiener said.


“Breast MRI using contrast agents has been around for about 15 years,” said Dr. Wiener. “Breast MRI isn’t widely used because there are concerns that it detects too many lesions that are not cancer, thereby causing too many women to undergo unnecessary biopsies. However we used a special computer program (computer assisted diagnosis), which helped us analyze the MRI images, looking at both morphology and kinetics. Morphology looks at the shape of the lesion, while kinetics looks at how quickly the contrast agent lights up the lesion then fades away. If the lesion is bright then washes out quickly, it usually indicates cancer,” he said. “By analyzing MRI using these and other factors, as well as carefully reviewing the mammograms and sonograms, we were able to more accurately answer the vital questions: does the patient have breast cancer and how extensive is the disease?” said Dr. Wiener.

The study appears in the March 2005 issue of the American Journal of Roentgenology.

Jason Ocker | EurekAlert!
Further information:
http://www.arrs.org

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Researchers shoot for success with simulations of laser pulse-material interactions

29.03.2017 | Materials Sciences

Igniting a solar flare in the corona with lower-atmosphere kindling

29.03.2017 | Physics and Astronomy

As sea level rises, much of Honolulu and Waikiki vulnerable to groundwater inundation

29.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>