Measuring a biological chemical called hyaluronan found naturally in joints and the fluid that lubricates cartilage might enable doctors to diagnose osteoarthritis of the knee and hip earlier or more accurately, a new study concludes. Improving diagnosis of the painful inflammatory disorder should become increasingly important as baby boomer age, doctors say.
The research, conducted at the University of North Carolina at Chapel Hill and in Johnston County, N.C., revealed that levels of the chemical, also known as HA, in blood samples corresponded with how advanced osteoarthritis was in a group of rural patients, both blacks and whites. "Our study shows statistically significant differences in average levels of serum hyaluronan (HA) between individuals with osteoarthritis of the knee as shown on X rays and those without knee or hip osteoarthritis," said study director Dr. Joanne M. Jordan. "Serum HA levels not only were associated with the presence of osteoarthritis but also showed a trend of increasing values as severity of the disease increased."
Jordan is associate professor of medicine and orthopaedics at the UNC School of Medicine. Also associate director of the Thurston Arthritis Research Center, she is principal investigator for the long-term Johnston County Osteoarthritis Project. That investigation is the largest of its kind ever done and involves more than 3,000 volunteers whose health and experiences with arthritis doctors follow and analyze. A report on the findings appears in the January issue of Arthritis & Rheumatism, a journal published by the American College of Rheumatology.
David Williamson | EurekAlert!
The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung
A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Health and Medicine
23.01.2017 | Physics and Astronomy
23.01.2017 | Process Engineering