Three commonly used drugs -- Prozac, Xenical and Meridia -- may help type 2 diabetes patients lose small amounts of weight, although long-term benefits are not clear, a new review of 22 studies suggests.
Prozac and Sarafem, known generically as fluoxetine, are most commonly prescribed as antidepressants. Xenical, the brand name for orlistat, blocks fat digestion in the intestines. Meridia, known generically as subtramine, is an appetite suppressant that works in the brain.
According to the systematic evidence review by Dr. Susan Norris of the U.S. Centers for Disease Control and Prevention and colleagues, patients taking fluoxetine had lost an average of 11 pounds (5.1 kilograms) 24 to 26 weeks after starting the therapy. Patients taking orlistat had lost an average of four and a half pounds (two kilograms) 12 to 57 weeks later, and those taking sibutramine had lost an average of 11 pounds 12 to 52 weeks later. “The magnitude of weight loss is modest, however, and the long-term health benefits remain unclear,” the review concludes.
Susan Norris | EurekAlert!
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