Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study finds markers for premature birth risk at the molecular level

10.02.2005


Raises potential for new prenatal test



For the first time, researchers have successfully profiled the amniotic fluid metabolome (the sum of all metabolic processes occurring in the amniotic fluid), in order to identify which women who have experienced preterm labor are also at risk for delivering a premature baby. With nearly one in eight babies in the U.S. born prematurely every year, and the problem of premature birth increasing, the need for tools that can identify preterm delivery risk has never been greater, experts say.

The news was announced today at the 25th annual Society for Maternal-Fetal Medicine (SMFM) meeting here. "We studied the amniotic fluid of three groups of patients – those with preterm labor who delivered at term, those with intra-amniotic inflammation who had both preterm labor and delivery, and those with no sign of inflammation who still had preterm labor and delivery," said Roberto Romero, M.D., lead study author and SMFM member. "We discovered that by using metabolic profiling, 96 percent of the time we could correctly identify the patients as belonging to the appropriate clinical group.


"A second study, in a different set of patients with a larger sample size, has already confirmed the effectiveness of our method. Until now, we have never had a way to predict the course of preterm labor with such accuracy. Metabolomic profiling has given us that tool," Dr. Romero said. "Prematurity is a common, serious, and growing problem in this country," said Nancy S. Green, M.D., medical director of the March of Dimes. "More research to identify and address the risk factors for prematurity are needed if we are to reverse this trend. The innovative nature of this study has earned it our annual award for the best research paper on prematurity."

Sanda Pecina | EurekAlert!
Further information:
http://www.marchofdimes.com/prematurity/

More articles from Studies and Analyses:

nachricht Antarctic Ice Sheet mass loss has increased
14.06.2018 | Technische Universität Dresden

nachricht WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Temperature-controlled fiber-optic light source with liquid core

In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.

Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...

Im Focus: Overdosing on Calcium

Nano crystals impact stem cell fate during bone formation

Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Towards universal influenza vaccines – is Neuraminidase underrated?

22.06.2018 | Life Sciences

Thermal Radiation from Tiny Particles

22.06.2018 | Physics and Astronomy

Polar ice may be softer than we thought

22.06.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>