In the first study of its kind, researchers say half of patients undergoing stem cell transplantation exhibit signs of delirium, but the warning signs are subtler and can be easily missed by clinicians. The study, which appears in the February 15, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society, says the level of distress, fatigue, and pain are associated with the severity of delirium.
Delirium is a temporary, acute change in a patients level of consciousness and cognition or perception that is caused by a medical condition. Classically, clinicians identify delirium by the presence of hallucinations, delusions, agitation, and disorientation. However, delirium appears to present itself in two prognostic categories: transient with less clinical significance and prolonged with greater clinical significance. Delirium is associated with a higher risk of falls, wound infections, and aspiration pneumonia. In cancer patients, delirium is further associated with increased risk of death during hospitalization and within five years of follow-up. While treatable with medications and appropriate care, delirium is underdiagnosed and undertreated, which can result in poor outcomes, patient and caregiver distress, and over-utilization of healthcare resources.
In order to improve clinical recognition of delirium in patients undergoing hematopoietic stem cell treatment (HSCT), Jesse R. Fann, M.D., M.P.H. of the University of Washingtons Department of Psychiatry and Behavioral Sciences and Fred Hutchinson Cancer Research Centers Division of Clinical Research and his colleagues followed 90 patients from before transplant to 30 days post-transplant and described the symptoms and time course as well as risk factors associated with delirium.
David Greenberg | EurekAlert!
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University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
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