The contrast agent iopromide, which has been used on more than 70 million patients worldwide, can be used for all types of CT imaging, regardless of the volume or dosage required, according to a new study by researchers from Brigham and Women’s Hospital and Harvard Medical School in Boston, MA.
For the study, researchers analyzed 29,508 patients who underwent contrast-enhanced CT with iopromide for a variety of diagnostic reasons. Of the patients studied, 29,297 experienced no adverse effects due to the contrast agent used. Of the 211 who did experience adverse effects, only four were rated as severe.
According to the study authors, iopromide has been available in the U.S. for about ten years and can be administered either intravenously or intraarterially, but up until now its safety has only been proven for selected procedures such as abdominal CT and angiography and only at specific dosage amounts. “We undertook the study to clarify some unresolved questions about intravenous contrast agents and to have a benchmark study regarding the safety of the agent in a large group of patients,” said Koenraad J. Mortelé , MD, lead author of the paper.
Jason Ocker | EurekAlert!
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The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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