Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study Highlights Importance of Worker Skin Exposure to Pesticides and Limitations of Measurement Methods

24.11.2004


Agricultural pesticide workers are not only exposed to pesticides from inhalation, but also through their skin. The dermal route of exposure to chlorpyrifos, a common agricultural pesticide, contributes substantially to workers’ total exposure, according to researchers from the Johns Hopkins Bloomberg School of Public Health and the U.S. Environmental Protection Agency (EPA), who analyzed agricultural test data provided by pesticide manufacturers. The study authors report that accurate methods for estimating dermal exposure are important because they form the basis for assessing and protecting worker health. The study is published in the current online issue of Annals of Occupational Hygiene.



“Although our study’s findings aren’t unexpected, they highlight the significance of dermal exposure among pesticide workers,” said Laura Geer, the study’s lead author and a PhD student in the Bloomberg School of Public Health’s Department of Environmental Health Sciences.

Geer explained that the EPA requires pesticide manufacturers to evaluate the potential for exposure to pesticide handlers. “Since there is a paucity of such data in the literature, we sought to mine these data. Our study demonstrates their utility and value to answer questions fundamental to dermal exposure and to protecting worker health,” she said. “For example, from these data, we were able to estimate the fraction of pesticide absorbed through the skin based on real-world agricultural worker monitoring.”


The authors analyzed data from five studies, including a total of 80 workers across nine states (Alabama, Virginia, Georgia, Texas, Arizona, Kentucky, Michigan, Florida and Ohio). The participants held a variety of pesticide-related jobs, including preparing pesticide formulations, loading the pesticide into application devices, applying the pesticide and inspecting crops after application.

The researchers found that dermal exposure represents a substantial portion of total exposure, even though exposure levels were found below current occupational health standards and guidelines. For nearly one-half of the workers monitored (34 out of 77) in this study, more chlorpyrifos was absorbed through the skin than was inhaled. The researchers compared methods for estimating worker exposure by comparing residues found on clothing to levels of pesticide metabolites in urine. They observed a substantial difference, indicating that researchers may not be able to precisely evaluate worker exposure using these methods.

This difference in estimates makes it difficult for researchers to reconcile exposure and dose, increasing the uncertainty in assessing worker risk and the development of effective protective strategies. The study authors recommend that additional work and research be done. The authors also note that their study demonstrates that the EPA’s Pesticide Registrant Database offers a unique and valuable resource to researchers for the purpose of improving methods for assessing exposure and protecting worker health.

“Worker dermal exposure is under-appreciated in the United States. Our study brings to the forefront the potential for workplace chemicals to be absorbed through the skin and the need to develop better methods to assess this exposure, so that ultimately we can prevent it and protect worker health,” said Timothy J. Buckley, PhD, MHS, associate professor in the Bloomberg School of Public Health’s Department of Environmental Health Sciences and the study’s senior author.

The study was supported by the United States Environmental Protection Agency.

L.A. Geer, N. Cardello, J. D. Roberts and T. J. Buckley, from the Johns Hopkins Bloomberg School of Public Health, co-authored the study. Additional co-authors from the U.S. Environmental Protection Agency were M. J. Dellarco, T.J. Leighton and R.P. Zendzian.

Kenna L. Lowe | EurekAlert!
Further information:
http://www.jhsph.edu

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Northern oceans pumped CO2 into the atmosphere

27.03.2017 | Earth Sciences

Fingerprint' technique spots frog populations at risk from pollution

27.03.2017 | Life Sciences

Big data approach to predict protein structure

27.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>