Surgeons at Western Pennsylvania Hospital report that laparoscopic surgery for obesity, known as Roux-en-Y gastric bypass, effectively improves unhealthy conditions associated with severe clinical obesity (or "morbid" obesity). The results, which were presented at the 69th Annual Scientific Meeting of the American College of Gastroenterology, reveal that after this surgery many patients are able to stop medications for a range of serious obesity-related health problems, including diabetes, sleep apnea, asthma, and high blood pressure.
"Comorbities associated with morbid obesity decrease life expectancy and impair quality of life," notes Pavlos Papasavas, M.D., one of the researchers at Western Pennsylvania Hospital. He and his colleagues followed 455 patients and collected data on medications used to treat comorbid diseases.
At follow-up, almost half (48.7 percent) of patients who took medications for high blood pressure preoperatively were now off medications. In addition, 92 percent of postoperative gastric bypass patients who took both oral medications for diabetes and insulin were off these medications at the time of their last follow-up. Another area of improvement was degenerative joint disease, with 32.5 percent of patients taking medications for this condition preoperatively, of whom 60 percent were off medications at follow-up. (Please see the attached abstract for a table summarizing all the findings.)
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At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
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Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
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UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
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