Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

’Weekend’ use matches daily drops for ’lazy eye’

02.11.2004


Adults who dispense eye drops daily to correct a child’s "lazy eye" take note: a new study from researchers at the Johns Hopkins Children’s Center and 29 other centers across North America finds that giving the drops just twice during the weekend is just as effective as administering them every day of the week.



In what is believed to be the first clinical trial comparing treatment regimens of atropine sulfate eye drops for the treatment of amblyopia, the investigators concluded that "there is no obvious advantage to the daily administration of atropine eye drops in either the speed of improvement or in the magnitude of improvement after four months of treatment," according to Michael Repka, M.D., the lead author of the study and a pediatric ophthalmologist at the Children’s Center. These findings are published by the Pediatric Eye Disease Investigator Group (PEDIG) in the November issue of Ophthalmology.

In the study, 168 children up to 7 years old with moderate amblyopia were randomly assigned to getting atropine eye drops either daily or on Saturday and Sunday only. After four months of treatment, children following both regimens were able to read an average of 2.3 lines higher on a standard eye chart. Additionally, 47 percent of children receiving daily drops and 53 percent getting weekend drops had vision in the amblyopic eye improve to normal levels by the four-month mark. This considerable degree of improvement is similar to that accomplished with daily eye patching, the mainstay of amblyopia treatment, the researchers note.


"The daily burden of administering drops usually falls on the parent, and if weekend eye drops are a good option, the regimen not only relieves some of this burden but may also encourage compliance with the treatment," Repka adds. "Compliance is very important, since timely and successful treatment for amblyopia in childhood can prevent lifelong visual impairment."

The most common cause of vision loss in children and young adults, amblyopia affects as many as 3 percent of children in the United States and usually begins in infancy or childhood. The condition is marked by poor vision in an otherwise healthy eye and occurs because the brain has learned to favor the other eye. Although the eye with amblyopia often looks normal, abnormal visual processing limits the development of a portion of the brain responsible for sight. The most common causes are crossed or wandering eyes, or significant differences in refractive error, such as farsightedness or nearsightedness, between the two eyes.

Atropine eye drops are designed to temporarily blur vision in the unaffected eye, thereby forcing the amblyopic eye to do most of the work. This helps strengthen the amblyopic eye and improves vision.

This research was conducted by the PEDIG at 30 clinical sites throughout North America and was funded by the National Eye Institute. The PEDIG focuses on studies of childhood eye disorders that can be implemented by both university-based and community-based practitioners as part of their routine practice.

Jessica Collins | EurekAlert!
Further information:
http://www.jhmi.edu

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

DGIST develops 20 times faster biosensor

24.04.2017 | Physics and Astronomy

Nanoimprinted hyperlens array: Paving the way for practical super-resolution imaging

24.04.2017 | Materials Sciences

Atomic-level motion may drive bacteria's ability to evade immune system defenses

24.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>