Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Ovarian cancer rates across Europe

25.10.2004


Incidence of ovarian cancer varies in Europe due to changing risk factors and improved treatment



Europe has one of the highest incidence rates of ovarian cancer in the world, making it an important public health issue. A new large-scale study of ovarian cancer trends found that while it is declining in most northern European countries, it is increasing in a few southern and eastern European countries. The study is published October 25, 2004 in the online edition of the International Journal of Cancer – the official journal of the International Union Against Cancer (UICC) – and is available online via Wiley InterScience.

Ovarian cancer rates may be affected by several factors. Hormonal factors include a woman’s age when menstruation began, the number of menstrual cycles she has had, and reaching menopause at a late age, In addition, nulliparity (never having children) or a low parity (e.g. having only borne children 1-2 times) has also been associated with increased risk of this type of cancer, while use of oral contraceptives has been associated with a decreased risk. Other factors include heredity, with ovarian cancer tending to run in families, and diet, although this relationship remains uncertain.


Researchers led by Freddie Bray of the International Agency for Research on Cancer in Lyon, France studied trends of ovarian cancer incidence and mortality in 28 European countries from 1953 until 2000 in order to try and understand the variation in trends among countries. They examined ovarian cancer data from 119 cancer registries in Europe according to year of diagnosis and age group, and mortality data from the World Health Organization (WHO) mortality database, again according to year of death and age group.

Results show an overall levelling of ovarian cancer rates across Europe, with declining incidence, and especially mortality rates, in most northern countries, particularly in younger age groups. In southern and eastern European countries, however, cancer incidence and mortality rates are increasing. The trends observed may be partially due to improvements in diagnostic techniques. Changing patterns of ovariectomy (removal of ovaries) and hysterectomy across different countries over time may have influenced the rates reported in the study. But the most important factor for declining cancer rates in some countries is most likely the spread of oral contraceptive use in younger women, which has taken place earlier and to a larger extent in northern Europe, the authors note. In addition, lower parity in some European countries has probably played a role in the increase in ovarian cancer, while changing lifestyle habits may have also influenced the incidence and outcome of the disease.

The authors conclude: "There are, therefore, several reasons to believe that the diverse patterns of ovarian cancer incidence and mortality trends registered in Europe over the last four decades are largely real, and can be explained by a combination of changing risk factors for incidence and, additionally for mortality, improving treatment."

David Greenberg | EurekAlert!
Further information:
http://www.interscience.wiley.com/journal/ijc.
http://www.wiley.com

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>