Researchers are conducting a groundbreaking new study that may help stroke patients regain greater use of their hands or arms through treatment with electrical stimulation. Preliminary results of the feasibility study that precedes this new study have shown that the use of electrical stimulation, called motor cortex stimulation, may be both safe and effective, according to Robert Levy, M.D., Ph.D., a neurosurgeon at Northwestern Memorial Hospital in Chicago. Dr. Levy presented this feasibility trial data at the Congress of Neurological Surgeons Wednesday in San Francisco.
The trial showed that study participants – stroke survivors suffering impaired hand or arm movement – who underwent physical rehabilitation accompanied by motor cortex stimulation showed greater improvement than participants who received physical rehabilitation alone. Twenty-four subjects participated in the feasibility study, 12 in the electrical stimulation group and 12 in the control group. "Participants in the electrical stimulation group experienced meaningful motor recovery gains," Dr. Levy says.
The study, sponsored by Northstar Neuroscience, Inc., is close to completing the follow-up period. Ongoing and further research is needed to validate these findings. Other sites in the study were the University of Illinois-Chicago, Rush University Medical Center, University of Arizona, Wayne State University, University of Minnesota and Kansas University. "It is our hope that by stimulating the surface of the brain we can permanently reverse paralysis and rekindle patients function, returning them to their normal lifestyle," says Dr. Levy, who is a professor at the Feinberg School of Medicine at Northwestern University and who is leading the study at Northwestern Memorial, which is being conducted in tandem with the Rehabilitation Institute of Chicago. "Unfortunately, when patients have had a stroke, there is not much we can currently offer beyond physical rehabilitation to improve their motor functions."
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