Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sister study opens nationwide

18.10.2004


A new study that will look at 50,000 sisters of women diagnosed with breast cancer opened today for enrollment across the United States. The Sister Study, conducted by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, will investigate environmental and genetic causes of breast cancer. The Sister Study is the largest study of its kind to look at breast cancer risk factors.



Women of all backgrounds and ethnic groups are eligible for the study if they are between the ages of 35 and 74; live in the United States; have never had breast cancer themselves; and have a sister living or deceased who has had breast cancer. To recruit a diverse group of volunteers and to ensure the results benefit all women, researchers are especially encouraging African-American, Latina, Native American, and Asian women, as well as women 60 and older, to join the Sister Study.

Sisters may be the key to unlocking breast cancer risk mysteries. Dale Sandler, Ph.D., Chief of the Epidemiology Branch at NIEHS and principal investigator of the Sister Study said, ’By studying sisters, who share the same genes, often had similar experiences and environments, and are at twice the risk of developing breast cancer, we have a better chance of learning what causes this disease. That is why joining the Sister Study is so important.’


At the beginning, volunteers will complete several questionnaires and provide a sample of their blood, urine, toenails, and household dust. ’With that, we’ll be able to look at how genes, activities of daily life, and exposure to different things in our environment are related to breast cancer risk,’ Dr. Sandler explained. ’We’ve made the process as easy and as convenient as possible, so we will come to you,’ she added.

The landmark study will stay in touch with the volunteers for 10 years and compare those who develop breast cancer with the majority who do not. While past studies have largely focused on hormones, reproductive health, and lifestyle, the Sister Study will take the most detailed look ever at how women’s genes, and things women come in contact with at home, at work, and in the community may influence breast cancer risk. Researches will study a range of environmental exposures, from personal care and household products, to workplace and other common exposures. ’Genes are important, but they don’t explain it all,’ said Dr. Sandler. ’The truth is that only half of breast cancer cases can be attributed to known factors.’ And, two known genes linked to breast cancer BRCA 1 and BRCA 2 play a role in only five to 10 percent of cases.

Women who may have felt helpless as they watched their sisters battle breast cancer now have an opportunity to help researchers learn more about causes of the disease. Dottie Sterling and Fluffy Reed both joined the study at the request of their youngest sister, Wish Martin, a breast cancer survivor in Maryland. ’Throughout my sister’s fight with breast cancer, we all prayed and prayed for healing and a swift recovery,’ said Sterling, a Sister Study volunteer in Ohio. ’Now my sister has been a breast cancer survivor for more than 13 years, and I could not be more proud. I see joining the Sister Study as my tribute to her strength and her faith.’

Many women have lost their sisters to breast cancer. "We need to find a cure for breast cancer and improve detection, diagnosis and treatment," said Patricia Bango, a participant in Virginia. "I joined the Sister Study as an advocate for my sister, Sally, who did not survive this devastating disease. I know her hope would have been that these efforts will help researchers find out what causes breast cancer."

The Sister Study opened in pilot states, including Arizona, Florida, Illinois, Missouri, North Carolina, Ohio, Rhode Island, and Virginia, earlier in 2004; but is now open for nationwide enrollment.

John Schelp | EurekAlert!
Further information:
http://www.niehs.nih.gov

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Researchers devise microreactor to study formation of methane hydrate

23.08.2017 | Materials Sciences

ShAPEing the future of magnesium car parts

23.08.2017 | Automotive Engineering

New insights into the world of trypanosomes

23.08.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>