Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

RFA effective for easing lung cancer symptoms; CT findings identified that verify successful RFA

01.10.2004


CT-guided radiofrequency ablation (RFA) is effective in easing the symptoms of lung tumors that cannot be removed by surgery, and enhancement pattern and changes in the size of the tumor as shown on CT are the most important factors for determining whether that ablation has been successful, according to a pair of independent studies in the October 2004 issue of the American Journal of Roentgenology.



For the first study, researchers from Caserta’s S. Sebastiano Hospital in Italy analyzed 33 patients with malignant lung cancer who could not undergo surgery and opted for CT-guided RFA instead. No major complications occurred for any patient during RFA, and all RFA sessions were deemed successful at follow-up CT.

According to Giuseppe Belfiore, MD, lead author of the article, the study was prompted by the feeling that an alternative to the usual therapies for lung cancer was strongly needed. "We see too many lung cancer patients who, inoperable for a number of different reasons, are left with few chances to obtain an effective palliation," said Dr. Belfiore. "We believe that a powerful alternative/complementary option is now available, although we believe that the full potential of RFA is still to be assessed. For sure, RFA allows a better quality of life for many inoperable patients," Dr. Belfiore added.


In a separate but related study, researchers from Chonbuk National University Hospital in South Korea determined that pattern enhancement--a difference in contrast between a tumor and the surrounding tissue--and changes in tumor size were the most important factors in judging the success of RFA for lung tumors on CT.

The researchers analyzed 21 patients who had undergone CT-guided RFA for lung tumors, nine of whom had complete ablations and 12 of whom had partial ablations performed. For the former group, the researchers found that the tumors were without any enhancement on short-term follow-up CT and that the size of the lesions had decreased by 40% after 12 months. For the partially ablated group, the tumors were enhanced to various degrees at short-term and the tumor size had increased after six months.

"During the past two years there have been increasing reports of RFA being performed for lung tumors, but, to our knowledge, no study has focused on the changes of ablated lung tumors on follow-up CT. Based on our results, we conclude that an enhancement pattern is a reliable finding for assessing the precise therapeutic efficacy of RFA on immediate follow-up CT. In addition, the knowledge of the size changes of the ablated tumors on long-term follow-up CT is helpful in assessing a tumor’s response to RFA in lung cancer," said Jeong Min Lee, MD, one of the authors of the study.

Jason Ocker | EurekAlert!
Further information:
http://www.arrs.org

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

What the world's tiniest 'monster truck' reveals

23.08.2017 | Life Sciences

Treating arthritis with algae

23.08.2017 | Life Sciences

Witnessing turbulent motion in the atmosphere of a distant star

23.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>