Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Group therapy does not improve survival In early-stage breast cancer patients

28.09.2004


First study in early-stage patients provides additional insight into how psychosocial interventions impact disease management



A new study shows that cognitive-existential group therapy (CEGT), a psychosocial intervention designed to improve the mood and attitude of patients with breast cancer, does not improve survival of women with early-stage disease. The study, to be published online September 27 in the Journal of Clinical Oncology, is the first to evaluate the impact of CEGT on the survival of early-stage breast cancer patients, and was conducted after previous studies of group therapy in women with metastatic breast cancer yielded mixed results.

"Although the results of this study do not demonstrate a survival benefit for patients receiving CEGT, they add to our body of knowledge of how psychosocial interventions can be used to help patients manage their disease," said David W. Kissane, MD, lead author and Chairman of the Department of Psychiatry and Behavioral Sciences at Memorial Sloan-Kettering Cancer Center. "We hope that this study will help to frame future research on how group therapy can be used to improve patients’ quality of life."


Group therapy was initially used in the oncology setting to help patients cope with the emotional challenges of living with cancer. However, more recently, a number of controlled clinical trials have sought to determine whether group therapy has any impact on survival in patients with metastatic breast cancer. An equal number of studies have shown evidence that supports or negates a survival benefit.

The current study evaluated the impact of CEGT on survival in patients with early-stage breast cancer, randomly assigning 303 women to receive adjuvant chemotherapy and 20 sessions of weekly group therapy plus 3 relaxation classes (n = 154), or adjuvant chemotherapy and 3 relaxation classes alone (n = 149). Researchers found no survival difference between patients receiving CEGT and those who did not. The most significant predictors of survival were the histology of the tumor and the number and location of lymph nodes to which cancer cells had spread.

An accompanying editorial by Pamela J. Goodwin, MD, MSc, FRCP(C) of the Samuel Lunenfeld Research Institute at Mount Sinai Hospital in Toronto, Canada, places the negative results of the study by Dr. Kissane and his colleagues in the context of the progress made in the larger field of psycho-oncology research. She argues that the study reinforces growing evidence that group therapy and other forms of psychosocial intervention are associated with improvement in mood, coping skills, and quality of life in women with breast cancer, and that the study provides direction for future research in the field of psycho-oncology.

"What is remarkable is the breadth of interventions that have been shown to be effective in one situation or another," Dr. Goodwin said. "Surprisingly little research has evaluated the impact of individual interventions in breast cancer, commonly used in the clinical setting. Formal evaluation of such interventions, as well as continuing research elucidating which interventions are most beneficial to different patient populations should form the basis for research in this area during the next decade. Toward this end, Kissane et al’s negative result should have a positive impact on the field of psycho-oncology as a whole."

Carrie Housman | EurekAlert!
Further information:
http://www.asco.org

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

Im Focus: Scientists improve forecast of increasing hazard on Ecuadorian volcano

Researchers from the University of Miami (UM) Rosenstiel School of Marine and Atmospheric Science, the Italian Space Agency (ASI), and the Instituto Geofisico--Escuela Politecnica Nacional (IGEPN) of Ecuador, showed an increasing volcanic danger on Cotopaxi in Ecuador using a powerful technique known as Interferometric Synthetic Aperture Radar (InSAR).

The Andes region in which Cotopaxi volcano is located is known to contain some of the world's most serious volcanic hazard. A mid- to large-size eruption has...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

New thruster design increases efficiency for future spaceflight

16.08.2017 | Physics and Astronomy

Transporting spin: A graphene and boron nitride heterostructure creates large spin signals

16.08.2017 | Materials Sciences

A new method for the 3-D printing of living tissues

16.08.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>