Researchers at Duke University Medical Center have discovered that otherwise healthy people who are prone to anger, hostility and mild to moderate depressive symptoms produce higher levels of a substance that promotes cardiovascular disease and stroke.
The substance, C-reactive protein (CRP), has garnered considerable attention for its role in both promoting and predicting cardiovascular disease and stroke in initially healthy people. It is produced by the liver in response to inflammation, and inflammation has recently been shown to underlie the plaque that forms inside arteries as they clog.
The Duke study is the first to link this combination of negative psychological attributes with higher levels of CRP in people without traditional risk factors for heart disease, said Edward Suarez, Ph.D., associate professor in the Duke Department of Psychiatry and Behavioral Sciences. Results of his study are published in the September, 2004, issue of the journal Psychosomatic Medicine. The study was funded by a grant from the National Heart, Lung and Blood Institute.
Becky Levine | EurekAlert!
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