A drug that is already being tested as an anticancer agent, especially in lymphoma, may also reduce the kidney disease that is a result of systemic lupus, according to a researcher at Wake Forest University Baptist Medical Center.
The drug, SAHA (suberoylanilide hydroxamic acid ), inhibited the onset of lupus-related kidney disease in mice with lupus, said Nilamadhab Mishra, M.D., an assistant professor of internal medicine - rheumatology, writing in the Sept. 15 issue of The Journal of Immunology, published online today.
Systemic lupus affects an estimated 1.5 million Americans, mostly women, and about half have kidney damage. In systemic lupus, the normally protective immune system attacks the bodys own organs, damaging kidneys, heart, lungs, brain, blood or skin. Most people with lupus have achy or swollen joints, frequent fevers and prolonged or extreme fatigue.
Robert Conn | EurekAlert!
Obstructing the ‘inner eye’
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Drone vs. truck deliveries: Which create less carbon pollution?
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Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....
A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...
Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision
Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...
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