An international study with nearly 900 patients co-infected with Human Immunodeficiency Virus (HIV) and hepatitis C virus (HCV) has shown that HCV can be treated effectively and safely, without compromising the patient’s HIV therapy.
Currently, HCV and resulting end-stage liver disease is the major cause of hospitalization and death in the more than one-third of HIV patients who are co-infected with HCV. While potent anti-viral therapies have prolonged the lives of HIV patients, HCV has emerged as the leading cause of liver disease and death in co-infected patients. And yet, most co-infected individuals go undiagnosed and untreated for their hepatitis.
Published in the July 29, 2004 edition of the New England Journal of Medicine, the study found that a combination therapy with peginterferon alfa-2a weekly injections plus oral ribavirin at a fixed 800 mg daily, achieved an overall 40 percent sustained virological response to HCV – the highest ever reported in a trial of co-infected patients. At the same time, investigators determined that the HCV treatment did not interfere with the effectiveness of HIV drugs.
Sue Pondrom | EurekAlert!
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The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
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