The incidence of first stroke in children with sickle cell disease in California has taken a nose-dive since 1998 and the likely reason is a program developed at the Medical College of Georgia to identify and treat kids at risk, a new study says.
The study by the University of California, San Francisco published in the current issue of Blood, looked at nearly two-thirds of the state’s children at high risk for stroke. Researchers found better than an 80 percent reduction in first strokes, a decline that began soon after the National Institutes of Health issued a clinical alert saying regular blood transfusions could dramatically reduce stroke risk.
"Among Californian children with sickle cell disease, stroke rates were relatively stable in the eight years leading up to the STOP study and then declined significantly (by more than 80 percent) over the subsequent two years," writes the research team, led by Dr. Heather J. Fullerton, neurologist.
Toni Baker | EurekAlert!
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