Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

$100,000 Grant Funds Further Study of Retinal Cell Transplantation

16.07.2004


The University of Utah’s John A. Moran Eye Center has received a $100,000 grant from the Stephen A. and Elaine Wynn Charitable Foundation to fund continued research into retinal cell transplantation. The research is expected to help set the stage for human clinical trials of treatments for a blinding eye disease known as Retinitis Pigmentosa (RP).



The funding will support the work of Raymond D. Lund, Ph.D., the Calvin S. and Janeal N. Hatch Presidential Endowed Chair and Professor of Ophthalmology and Visual Sciences at the University of Utah. Groundbreaking research published by Lund’s group in 2002 demonstrated that vision could be preserved in rats born with vision loss similar to the human disease Retinitis Pigmentosa by transplanting healthy cells from human biopsies into their eyes.

“Our initial research showed, in essence, that rats who would have been blind without a transplant were able to discriminate patterns as well as rats with normal vision. Our idea to transplant new cells into the eye to sustain and nurture defective cells is a novel approach that has proven successful beyond expectations,” said Lund.


Before attempting this type of research in humans, however, Lund says there are more questions that need to be answered. Specifically, new research funded by the Wynn Foundation will evaluate whether any safety issues emerge, how late in the animal’s life transplantation can be effective, and how to translate the laboratory experience to the clinic.

“Once we’re satisfied that all of our questions are answered we’ll begin planning for limited human clinical trials,” said Lund. He emphasizes that the trials will include a very small number of RP patients.

According to the Foundation Fighting Blindness (www.blindness.org), patients with RP often experience a ring of vision loss in their mid-periphery with small islands of vision in their very far periphery. Other patients report the sensation of tunnel vision, as though they see the world through a straw. Many RP patients retain a small degree of central vision throughout their life.

Since the opening of the John A. Moran Eye Center in 1993, the Stephen A. and Elaine Wynn Charitable Foundation has provided the center with nearly $500,000 in funding through grants. The Wynn family has also played an important role in fundraising for the center and Mr. Wynn sits on the center’s Advisory Board.

“The goal of the foundation is to provide seed money to scientists and programs whose research is nearing human clinical trials. We’ve been especially impressed with Dr. Lund and his team of scientists because of the great sensitivity they’ve shown to patients suffering from blinding eye diseases. Dr. Lund recognizes that for patients and their families this type of research is a race toward treatment,” according to Steven Dezii, a foundation trustee and spokesperson.

| newswise
Further information:
http://www.hsc.utah.edu

More articles from Studies and Analyses:

nachricht Amputees can learn to control a robotic arm with their minds
28.11.2017 | University of Chicago Medical Center

nachricht The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>