Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Study links virus to aggressive breast cancers

12.07.2004


A new study finds increasing evidence a virus may play a role in breast cancer. The study, published July 12, 2004 in the online edition of CANCER, a peer-reviewed journal of the American Cancer Society, finds nearly three-quarters of a small sample of Tunisian breast cancer patients showed evidence of a virus similar to one known to cause breast cancer in mice, twice the rate seen in women in the United States. A free abstract of the study will be available via Wiley InterScience.



Viruses play a primary role in the development of several cancers, such as the human T-cell lymphotropic virus and adult T-cell leukemia/lymphoma or human herpes virus 8 (HHV8) and Kaposi sarcoma (KS). Geographic variability has also been noted in these cancer-promoting viruses. For example, KS and HHV8 are least common in the U.S. and more common in the Mediterranean and Central African regions.

Existing epidemiological evidence and animal models suggest that a virus may be involved in the development of certain breast cancers. Previous analyses of human breast tissue samples found viral sequences from the mouse mammary tumor virus (MMTV) in a large percentage of breast cancers but not in normal tissue. MMTV may be spread by a species of house mouse that is extremely common in North Africa but less so in the U.S. Studies show that some colonies of these mice are commonly infected with MMTV.


Dr. Paul H. Levine from The George Washington University School of Public Health and Health Services and his colleagues compared 38 samples of breast tumors from patients treated in Tunisia with samples from several other countries.

The authors found that on independent review by two laboratories, a significantly higher proportion of samples from Tunisia tested positive for an MMTV-specific genetic sequence compared to samples from North America, Europe and South America. While 74 percent of Tunisian samples tested positive, other studies reported only 36 percent positive cases from the U.S., 38 percent from Italy, 42 percent from Australia, and 31 percent from Argentina.

Further analysis showed that 89 percent of the MMTV-positive samples were from clinically and histologically aggressive tumors, including trends toward shorter disease-free intervals. The authors conclude: "These findings provide increasing evidence for a human breast cancer virus with geographic differences in prevalence."

David Greenberg | EurekAlert!
Further information:
http://www.wiley.com
http://www.interscience.wiley.com/cancer-newsroom

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>