Study results published in the August issue of the journal Cancer reinforce previous findings that the laminin-8 genes and the resulting protein may be highly valuable targets in the fight against malignant brain tumors.
Researchers at Cedars-Sinai’s Maxine Dunitz Neurosurgical Institute report that over-expression of laminin-8 can be used as a predictor of a tumor’s grade, its potential for recurrence, and the patient’s length of survival. This follows their earlier findings that laminin-8 is up-regulated in the most aggressive brain tumors, glioblastoma multiforme (GBM), and that the gene promotes the tumor cells’ ability to invade neighboring tissue.
The thin “basement membrane” that lies beneath the surface layer of blood vessels contains proteins called laminins. Fifteen laminins have been identified to date. The Cedars-Sinai researchers found that during tumor progression, laminin-9, which is expressed weakly in normal brain tissue and low-grade glial tumors, switched to laminin-8, and the level of expression of the laminin-8 increased significantly, depending on brain tumor grade.
Sandy Van | Cedars-Sinai
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In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...
Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
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21.06.2018 | Earth Sciences