Moderate exercise in conjunction with common dietary supplements significantly reduce the risk of atherosclerosis because, combined, they boost the bodys production of nitric oxide, which protects against a variety of cardio-vascular disorders, a new UCLA study led by 1998 Nobel Laureate in medicine Louis J. Ignarro shows.
The study, "Long Term Beneficial Effects of Physical Training and Metabolic Treatment on Atherosclerosis in Hypercholesterolemic Mice," will be published the week of May 24 in the online edition of the Proceedings of the National Academy of Sciences (www.pnas.org). It found that moderate exercise reduced the development of atherosclerosis, or hardening of the arteries, in mice that are genetically prone to heart disease, because exercise alone has been shown to increase nitric oxide in the body. Adding the amino acid L-arginine and the anti-oxidants Vitamins C and E to the mix, however, significantly magnified the effect, said Ignarro, professor of molecular and medical pharmacology in the David Geffen School of Medicine at UCLA.
And whats good for mice is good for humans, said Ignarro, who shared the Nobel Prize for his discoveries in the role that nitric oxide (NO) plays in the cardiovascular system.
Enrique Rivero | EurekAlert!
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