Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

In male monkeys, too much soy has adverse effects

03.05.2004


Researchers from Wake Forest University Baptist Medical Center Report



While soy may be beneficial to women in a variety of ways, research in monkeys suggests that it could have an adverse effect on the behavior of men, according to researchers from Wake Forest University Baptist Medical Center.

Reporting in the current issue of the scientific journal Hormones and Behavior, the researchers found that in male monkeys, "long-term consumption of a diet rich in soy isoflavones can have marked influences on patterns of aggression and social behavior." Isoflavones are a naturally occurring plant estrogen in soy protein.


"Although considerable attention has been directed at the potentially beneficial effects of isoflavones in reducing the risk of various cancers, osteoporosis, cardiovascular disease and postmenopausal symptoms, less effort has been invested in characterizing neurobehavioral effects," according to the study.

People have the concept that soy is only beneficial, said Jay R. Kaplan, Ph.D., professor of comparative medicine and anthropology, one of the investigators. "There is the thought that what is good for some is good for all and more is better."

But this research points out that not only does the dose make a difference, but so does the sex of the consumer, Kaplan said, adding that the study is consistent with emerging literature showing that soy can have a negative impact on the behavior of male rodents. Previous studies have shown no difference in aggression in females given large doses of soy, Kaplan said.

The study was done over 15 months with adult male monkeys who were divided into three groups and fed different amounts and types of protein. One group had about 125 mg of isoflavones a day. The second group had half that amount, and the third group’s protein came from milk and animal sources.

"In the monkeys fed the higher amounts of isoflavones, frequencies of intense aggressive and submissive behavior were elevated," according to the study. "In addition, the proportion of time spent by these monkeys in physical contact with other monkeys was reduced by 68 percent, time spent in proximity to other monkeys was reduced 50 percent and time spent alone was increased 30 percent."

Isoflavone levels of 125 mg per day are higher than amounts consumed by many Asians, who typically eat more soy than other populations. But, the isoflavone levels are comparable to levels found in many dietary supplements sold in the United States.

The FDA approved a statement in 1999 that said, "25 grams of soy protein a day, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease." Soy sales have grown from $940 million in 1990 to a projected $4 billion this year. Kaplan said that soy is the most widely used botanical by pre- and postmenopausal women.

"To the best of our knowledge, the present study may be the first to demonstrate that long-term consumption of isoflavones can alter patterns of agonistic and social behavior in primates," the researchers reported. "The present findings suggest that careful attention will be required to balance beneficial and potentially adverse effects."



Other researchers in the study included Michael R. Adams, D.V.M., professor of pathology, and Thomas C. Register, Ph.D., associate professor of pathology, at Wake Forest Baptist, as well as two researchers from Lehigh University’s Department of Biological Sciences.

The research was funded by NIH grants and a grant from the HF Guggenheim Foundation.

Media Contacts: Karen Richardson, krchrdsn@wfubmc.edu; Shannon Koontz, shkoontz@wfubmc.edu; at 336-716-4587

About Wake Forest University Baptist Medical Center: Wake Forest Baptist is an academic health system comprised of North Carolina Baptist Hospital and Wake Forest University School of Medicine. It is licensed to operate 1,282 acute care, psychiatric, rehabilitation and long-term care beds and is consistently ranked as one of "America’s Best Hospitals" by U.S. News & World Report.

Karen Richardson | EurekAlert!
Further information:
http://www.wfubmc.edu/

More articles from Studies and Analyses:

nachricht Win-win strategies for climate and food security
02.10.2017 | International Institute for Applied Systems Analysis (IIASA)

nachricht The personality factor: How to foster the sharing of research data
06.09.2017 | ZBW – Leibniz-Informationszentrum Wirtschaft

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>