Although women normally have androgens – so-called "male" hormones – circulating in their bloodstreams, excessive levels can cause a variety of symptoms including acne, weight gain, excessive hair growth (hirsutism), menstrual dysfunction, and infertility.
Hirsutism – the growth of coarse hair in patterns similar to those of men – has long been considered the key marker for androgen excess. Physicians have had difficulty providing a firm diagnosis and identifying underlying causes, however, because a number of disorders can cause hirsutism, not all women with hirsutism have evidence of androgen excess, and not all patients who have androgen excess disorders suffer from hirsutism. Determining the most effective treatment has been challenging, too. While most women have been treated with single-agent hormone therapy, a combination approach has been suggested as a better alternative, but comparison studies have been conducted in only small samples of patients.
Now a long-term study – perhaps the largest of its kind to date – identifies the most common causes of androgen excess in women and compares therapeutic approaches, showing that combination hormonal therapy can improve most symptoms. Researchers at Cedars-Sinai Medical Center and the University of Alabama at Birmingham report their findings in the February issue of the Journal of Clinical Endocrinology and Metabolism in an "Extensive Personal Experience" article.
Sandra Van | Van Communications
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
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