Scientists have developed biodegradable polymers that can mimic the ability of white blood cells to target inflamed blood vessel walls, according to a new study led by Ohio University researchers. The finding could be the first step in developing drugs that suppress specific sites of inflammation in medical conditions such as arthritis, heart disease and inflammatory bowel disease.
Researchers found that biodegradable beads coated with targeting molecules can travel through the bloodstream and effectively stick to the site of tissue inflammation, a symptom of various diseases, according to the study, which will be published in the Dec. 23 issue of the journal Proceedings of the National Academy of Sciences. Scientists are interested in drugs made from biodegradable polymers because they can be easily prepared, have a long shelf life and can be designed to release specific doses of medication, according to the study.
When the body suffers from a bacterial infection or a wound, the white blood cells, or leukocytes, adhere to the site to treat the problem. But in inflammatory diseases such as arthritis, heart disease or inflammatory bowel disease, leukocytes accumulate in an area where they arent needed and cause or progressively worsen the disease.
Andrea Gibson | EurekAlert!
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Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.
For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...
What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.
To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...
The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....
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Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision
Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...
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