Scientists have developed biodegradable polymers that can mimic the ability of white blood cells to target inflamed blood vessel walls, according to a new study led by Ohio University researchers. The finding could be the first step in developing drugs that suppress specific sites of inflammation in medical conditions such as arthritis, heart disease and inflammatory bowel disease.
Researchers found that biodegradable beads coated with targeting molecules can travel through the bloodstream and effectively stick to the site of tissue inflammation, a symptom of various diseases, according to the study, which will be published in the Dec. 23 issue of the journal Proceedings of the National Academy of Sciences. Scientists are interested in drugs made from biodegradable polymers because they can be easily prepared, have a long shelf life and can be designed to release specific doses of medication, according to the study.
When the body suffers from a bacterial infection or a wound, the white blood cells, or leukocytes, adhere to the site to treat the problem. But in inflammatory diseases such as arthritis, heart disease or inflammatory bowel disease, leukocytes accumulate in an area where they arent needed and cause or progressively worsen the disease.
Andrea Gibson | EurekAlert!
Amputees can learn to control a robotic arm with their minds
28.11.2017 | University of Chicago Medical Center
The importance of biodiversity in forests could increase due to climate change
17.11.2017 | Deutsches Zentrum für integrative Biodiversitätsforschung (iDiv) Halle-Jena-Leipzig
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications
Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
Physicists in the Laboratory for Attosecond Physics (run jointly by LMU Munich and the Max Planck Institute for Quantum Optics) have developed an attosecond electron microscope that allows them to visualize the dispersion of light in time and space, and observe the motions of electrons in atoms.
The most basic of all physical interactions in nature is that between light and matter. This interaction takes place in attosecond times (i.e. billionths of a...
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