Almost two out of three children with severe asthma are boys. But women account for more than two out of three adults with severe asthma. And no one really knows why. Those are some of the most striking results of a cross-sectional study of severe asthma by researchers from National Jewish Medical and Research Center being published in the October issue of the journal Chest. The research team, led by Joseph Spahn, M.D., also found that children with severe asthma had surprisingly good airflow in and out of their lungs, which could lead to misdiagnosis and undertreatment of seriously ill patients.
"Our findings highlight many of the significant differences between severe asthma in children and adults," said Dr. Spahn. "We hope they will spur further research that can lead to a better understanding and better treatment of this disease."
People with severe asthma, whose asthma remains uncontrolled in spite of high doses of medication, represent 5 percent to 10 percent of the estimated 20 million asthma patients in the United States. But they are important in terms of suffering, medical costs and difficulty finding effective treatments. Dr. Spahn and his colleagues examined a variety of demographic and biological data for 275 patients with severe asthma who had been referred to National Jewish.
William Allstetter | National Jewish News
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