Led by John B. Kostis, MD, the John G. Detwiler professor of cardiology, professor of medicine and chair, department of medicine, UMDNJ-Robert Wood Johnson Medical School, this post-hoc analysis of the five-year 10,001 patient TNT study that was funded by Pfizer, Inc., was published in the May 2008 issue of the Journal of Clinical Hypertension.
“People who have both high cholesterol and high blood pressure are at greater risk for cardiovascular disease than those with either condition alone.Yet, a minority of patients with both conditions is treated to currently recommended targets. In one study less than a third of such patients were treated and only one in ten were treated to target,” said Dr. Kostis. “The analysis reported today reminds us that intensive management of both cholesterol and blood pressure, can significantly reduce the risk of heart attacks and strokes.”
Among the 10,001 patients of TNT, 9,739 who had both LDL cholesterol and systolic blood pressure measured at three months after randomization, were included in this analysis. All patients received cholesterol-lowering therapy with atorvastatin calcium (Lipitor®) 80 mg or 10 mg. More than 95 percent of patients in this analysis also were receiving antihypertensive therapy.As reported in the published analysis, patients were divided into groups based on LDL levels (73 mg/dL and lower; 74 to 94 mg/dL; or 95 mg/dL and higher) and systolic blood pressure (140 mmHg and higher, or lower than 140 mmHg) at three months. During a median follow-up of 4.9 years, patients with the lowest LDL and the lowest BP had the lowest risk of major cardiovascular events. For each of the three LDL groups, the rate of cardiovascular events was lower in patients whose systolic blood pressure (SBP) was below 140 mmHg. The benefit of SBP
“Overall, this study provides new evidence of the importance of controlling both dyslipidemia and hypertension” said Dr. Kostis. “However, controlling other risk factors, especially smoking, is still essential to reducing the risk of heart attack and stroke.”
To interview Dr. Kostis, contact Jennifer Forbes at email@example.com or 732-235-6356.
As one of the eight schools of the University of Medicine and Dentistry of New Jersey with 2,500 full-time and volunteer faculty, Robert Wood Johnson Medical School encompasses 22 basic science and clinical departments, hosts centers and institutes including The Cancer Institute of New Jersey, the Child Health Institute of New Jersey, the Center for Advanced Biotechnology and Medicine, the Environmental and Occupational Health Sciences Institute, and the Stem Cell Institute of New Jersey. The medical school maintains educational programs at the undergraduate, graduate and postgraduate levels for more than 1,500 students on its campuses in New Brunswick, Piscataway, and Camden, and provides continuing education courses for health care professionals and community education programs.
Jennifer Forbes | newswise
Smart Data Transformation – Surfing the Big Wave
02.12.2016 | Fraunhofer-Institut für Angewandte Informationstechnik FIT
Climate change could outpace EPA Lake Champlain protections
18.11.2016 | University of Vermont
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
08.12.2016 | Materials Sciences
08.12.2016 | Materials Sciences
08.12.2016 | Physics and Astronomy