Molecular and statistical genetic studies in 15 Finnish families have shown that there is a substantial genetic component in musical aptitude. Musical aptitude was determined using three tests: a test for auditory structuring ability (Karma Music test), and the Seashore pitch and time discrimination subtests. The study represents the first systematic molecular genetic study that aims in the identification of candidate genes associated with musical aptitude.
The identified regions contain genes affecting cell extension and migration during neural development. Interestingly, an overlapping region previously associated with genetic locus for dyslexia was found raising a question about common evolutionary background of music and language faculties. The results show that musical aptitude is likely to be regulated by several predisposing genes/variants.
“The identification of genes/genetic variants involved in mediating music perception and performance would offer new tools to understand the role of music in human brain function, human evolution and its relationship to language faculty”, says the leader of the study, Dr. Irma Järvelä from the University of Helsinki.
The study was performed in collaboration with the University of Helsinki, Sibelius Academy, Helsinki, Finland, The Family Federation of Finland, Red Cross Finland Blood Service, and Southwest Foundation for Biomedical Research, San Antonio, USA.
The study can be read at http://jmg.bmj.com.
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Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
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