Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Short Arms and Legs Linked to Risk of Dementia

06.05.2008
People with shorter arms and legs may be at a higher risk for developing dementia later in life compared to people with longer arms and legs, according to a study published in the May 6, 2008, bonus issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers say the association between short limbs and dementia risk may be due to poor nutrition in early life, which can affect limb growth.

Several studies have shown that early life environment plays an important role in susceptibility to chronic disease later in life. “Body measures such as knee height and arm span are often used as biological indicators of early life deficits, such as a lack of nutrients,” said Tina L. Huang, PhD, who was with Johns Hopkins University in Baltimore, MD, when the study started.

Huang is now with the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston, MA. “Because the development of the brain region most severely affected by Alzheimer’s disease coincides with the greatest change in limb length, we thought it was possible that men and women with shorter limbs could be at greater risk for developing dementia and Alzheimer’s disease.”

Researchers from the Cardiovascular Health Cognition Study followed 2,798 people for an average of five years and took knee height and arm span measurements. Most participants were white with an average age of 72. By the end of the study, 480 developed dementia.

Researchers found women with the shortest arm spans were 1.5 times more likely to develop dementia and Alzheimer’s disease than women with longer arm spans. For every inch longer a woman’s leg, the risk of dementia and Alzheimer’s disease was reduced by 16 percent.

In men, only arm span was associated with a lower risk of dementia. With every increased inch in arm span, men had a six-percent increase in risk of dementia. The associations with such measures in men and women were stronger toward Alzheimer’s disease compared to other types of dementia.

Huang says there is a strong correlation between height and socioeconomic background, and trends are reflected as early as the first two years of life. “Reduced height for age, or stunting, is thought to be most closely tied to environment and the quality of diet in early life, which corresponds with periods of the fastest leg growth,” said Huang. “As a result, environment in the first years of life may play an important role in determining future dementia risk.”

“Our findings are consistent with other studies that have been done in Korean populations, where shorter limb length was associated with greater risk of dementia,” said Huang.

The study was supported by grants from the National Institute on Aging, the National Heart, Lung and Blood Institute and the National Institutes of Health.

The American Academy of Neurology, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer’s disease, epilepsy, Parkinson’s disease, and multiple sclerosis.

Angela Babb | American Academy of Neurology
Further information:
http://www.aan.com

More articles from Studies and Analyses:

nachricht Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung

nachricht Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

New insights into the world of trypanosomes

23.08.2017 | Life Sciences

New Test for Rare Immunodeficiency

23.08.2017 | Life Sciences

Cholesterol-lowering drugs may fight infectious disease

22.08.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>