The new findings should help public health officials more quickly and accurately determine which strains to include in the annual flu vaccine.
The study, supported in part by the National Institutes of Health (NIH), appears online in advance of print in the journal Nature.
The researchers analyzed full gene sequences of seasonal influenza virus samples collected from the world’s temperate regions north and south of the equator. Their data comprised full genetic sequences of 1,302 isolates of influenza A virus collected over 12 years from New Zealand and New York state.
By quantifying the degree of genetic diversity among the strains’ subtypes, gene segments and geographic locations, the researchers were able to detect patterns indicating that virus strains do not persist from one flu season to the next in the temperate regions. Therefore, the researchers deduced, new flu strains emerge annually from the tropics.
The international team of researchers included Jeffery K. Taubenberger, M.D., Ph.D., of the National Institute of Allergy and Infectious Diseases, NIH; Cecile Viboud, Ph.D., of NIH’s Fogarty International Center; and Edward C. Holmes, Ph.D., of Pennsylvania State University, who received funding from the National Institute of General Medical Sciences, NIH. The gene sequence information is stored in an NIAID-supported and publicly accessible database, the Influenza Genome Sequencing Project http://www3.niaid.nih.gov/research/resources/mscs/Influenza/.
ARTICLE: A Rambaut et al. The genomic and epidemiological dynamics of human influenza A virus. Nature DOI: 10.1038/nature06945 (2008).
WHO: NIAID Director Anthony S. Fauci, M.D., is available to comment. Jeffery K. Taubenberger, M.D., Ph.D., Laboratory of Infectious Diseases, NIAID, is also available.
CONTACT: To schedule interviews, contact Anne A. Oplinger in the NIAID Office of Communications and Government Relations at 301-402-1663 or firstname.lastname@example.org.
NIAID is a component of the National Institutes of Health. NIAID supports basic and applied research to prevent, diagnose and treat infectious diseases such as HIV/AIDS and other sexually transmitted infections, influenza, tuberculosis, malaria and illness from potential agents of bioterrorism. NIAID also supports research on basic immunology, transplantation and immune-related disorders, including autoimmune diseases, asthma and allergies.
The National Institutes of Health (NIH)--The Nation's Medical Research Agency--includes 27 Institutes and Centers and is a component of the U. S. Department of Health and Human Services. It is the primary federal agency for conducting and supporting basic, clinical and translational medical research, and it investigates the causes, treatments and cures for both common and rare diseases.
News releases, fact sheets and other NIAID-related materials are available on the NIAID Web site at http://www.niaid.nih.gov.
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
24.10.2016 | Earth Sciences
24.10.2016 | Life Sciences
24.10.2016 | Physics and Astronomy