“Endovascular repair of abdominal aortic aneurysms has become a viable alternative treatment to open surgery for many patients. Endoleak development represents a complication of endovascular aortic aneurysm repair and is characterized by blood flow outside the stent-graft lumen but within the aneurysm sac,” said Rolf Wyttenbach, MD, lead author of the study.
“Patients after EVAR need livelong imaging surveillance to detect endoleaks. CT is most commonly used for imaging follow-up of these patients. , A few prior studies suggested that MRI may be superior to CT for the detection of endoleaks. However, these studies mostly used single or 4-row MDCT and standard gadolinium contrast media for MR imaging,” he said.
The study consisted of 43 patients who had undergone EVAR. Each of the patients had both MDCT and MRI within one week of the procedure. According to the study, MRI was performed using a high relaxivity contrast medium and for MDCT, an iodine containing agent was used. Upon the completion of the study, two observers evaluated MRI and MDCT separately.
The study showed that 21 endoleaks were detected in 18 patients. Sensitivity, specificity and accuracy for endoleak detection were 100%, 96% and 98% for reader 1 and 90%, 81% and 85% for reader 2 on MRI and 48%, 96% and 74% for both readers on MDCT.
“The results indicate that MR is a good choice for diagnosing endoleaks. In addition, MRI does not expose the patients to radiation and the MR contrast agent is less nephrotoxic in the clinically used dose compared to iodinated contrast agents used for CT. For this reason MRI may become a preferred imaging modality to follow-up patients after endovascular aneurysm repair,” said Dr. Wyttenbach.
Necoya Tyson | EurekAlert!
New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)
Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
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26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy