Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Maternal obesity not strongly linked to obesity in offspring says study

11.03.2008
Professor Debbie Lawlor and colleagues used two approaches to test the ‘developmental overnutrition’ hypothesis which asserts that if a woman is overweight during pregnancy, high sugar and fat levels in her body might permanently affect her growing baby’s appetite control and metabolism, thus increasing the child’s risk of becoming obese in later life.

First, the researchers asked whether offspring fat mass is more strongly related to maternal BMI than paternal BMI; it should be if the hypothesis is true.

Second, they asked whether a genetic indicator of maternal fatness – the “A” variant of the FTO gene – is related to offspring fat mass. A statistical association between maternal FTO genotype and offspring fat mass, after taking account of the offspring’s own FTO genotype, would support the developmental nutrition hypothesis.

The researchers used data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to look for associations between the pre-pregnancy BMI of the parents of about 4,000 children and the children’s fat mass at ages nine to eleven years.

They found that both maternal and paternal BMI were positively associated with offspring fat mass but the effect of maternal BMI was greater than the effect of paternal BMI. However, the greater effect of maternal BMI was too weak to explain the recent obesity epidemic.

When the researchers examined maternal FTO genotypes and offspring fat mass, there was no statistical evidence to suggest that differences in offspring fat mass were related to the maternal FTO genotype.

Professor Lawlor said: “If true, the developmental over-nutrition hypothesis has wide-reaching public health implications as it means the obesity epidemic could accelerate across generations and continue to do so for some time, even with effective obesity prevention programmes.

“However, our study indicates that developmental overnutrition has not been a major driver of the recent obesity epidemic. Therefore, interventions that aim to improve people’s diet and to increase their physical activity levels could slow or even halt the epidemic.”

Hannah Johnson | EurekAlert!
Further information:
http://www.bristol.ac.uk

More articles from Studies and Analyses:

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

nachricht Reusable carbon nanotubes could be the water filter of the future, says RIT study
30.03.2017 | Rochester Institute of Technology

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Strathclyde-led research develops world's highest gain high-power laser amplifier

The world's highest gain high power laser amplifier - by many orders of magnitude - has been developed in research led at the University of Strathclyde.

The researchers demonstrated the feasibility of using plasma to amplify short laser pulses of picojoule-level energy up to 100 millijoules, which is a 'gain'...

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

Reptile vocalization is surprisingly flexible

30.05.2017 | Life Sciences

EU research project DEMETER strives for innovation in enzyme production technology

30.05.2017 | Power and Electrical Engineering

New insights into the ancestors of all complex life

29.05.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>