Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Maternal obesity not strongly linked to obesity in offspring says study

11.03.2008
Professor Debbie Lawlor and colleagues used two approaches to test the ‘developmental overnutrition’ hypothesis which asserts that if a woman is overweight during pregnancy, high sugar and fat levels in her body might permanently affect her growing baby’s appetite control and metabolism, thus increasing the child’s risk of becoming obese in later life.

First, the researchers asked whether offspring fat mass is more strongly related to maternal BMI than paternal BMI; it should be if the hypothesis is true.

Second, they asked whether a genetic indicator of maternal fatness – the “A” variant of the FTO gene – is related to offspring fat mass. A statistical association between maternal FTO genotype and offspring fat mass, after taking account of the offspring’s own FTO genotype, would support the developmental nutrition hypothesis.

The researchers used data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to look for associations between the pre-pregnancy BMI of the parents of about 4,000 children and the children’s fat mass at ages nine to eleven years.

They found that both maternal and paternal BMI were positively associated with offspring fat mass but the effect of maternal BMI was greater than the effect of paternal BMI. However, the greater effect of maternal BMI was too weak to explain the recent obesity epidemic.

When the researchers examined maternal FTO genotypes and offspring fat mass, there was no statistical evidence to suggest that differences in offspring fat mass were related to the maternal FTO genotype.

Professor Lawlor said: “If true, the developmental over-nutrition hypothesis has wide-reaching public health implications as it means the obesity epidemic could accelerate across generations and continue to do so for some time, even with effective obesity prevention programmes.

“However, our study indicates that developmental overnutrition has not been a major driver of the recent obesity epidemic. Therefore, interventions that aim to improve people’s diet and to increase their physical activity levels could slow or even halt the epidemic.”

Hannah Johnson | EurekAlert!
Further information:
http://www.bristol.ac.uk

More articles from Studies and Analyses:

nachricht New study from the University of Halle: How climate change alters plant growth
12.01.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Disarray in the brain
18.12.2017 | Universität zu Lübeck

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

Im Focus: A thermometer for the oceans

Measurement of noble gases in Antarctic ice cores

The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Polymers Based on Boron?

18.01.2018 | Life Sciences

Bioengineered soft microfibers improve T-cell production

18.01.2018 | Life Sciences

World’s oldest known oxygen oasis discovered

18.01.2018 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>