“This is the first study to focus on this high risk—and highly unstudied—group.” said Yale School of Public Health Associate Professor Judith Lichtman, co-principal investigator of the study. “There have been no large, prospective studies of this population, even though the death toll is comparable to that from breast cancer.”
She said the research team is exploring what accounts for premature heart disease in women and why they experience worse outcomes than men of similar age with heart disease.
The four-year grant will support the study of 2,000 women age 55 and younger with 1,000 men for comparison. The multi-site study bridges disciplines from basic biology and clinical sciences to psychology and health services research.
Although women under age 55 with heart attacks represent a small proportion of all patients with heart disease, they account for about 40,000 hospitalizations each year. About 8,000 women under the age of 55 die of heart disease annually, ranking it among the major causes of death in this group. While most women in this age group are protected from heart disease, notes Lichtman, prior research indicates that young women have a much greater risk of dying after a heart attack than men of the same age.
The study addresses questions ranging from genetics and clinical care to outcomes, including: How are outcomes of women different from those of men" What are the genetic, demographic, psychosocial, and behavioral factors that contribute to premature heart disease in women" How do delays in clinical presentation and treatment affect the risk and outcomes of women" Do women get the same quality of care as men"
“Despite the increasing focus on women with heart disease in recent years, we know little about heart disease in this population,” said principal investigator Harlan M. Krumholz, M.D., the Harold H. Hines, Jr. Professor of Medicine and Epidemiology and Public Health at Yale School of Medicine. “Since young women with heart disease are relatively rare at any one hospital, we have assembled an unprecedented network of almost 100 sites nationwide to identify and enroll women for this ground-breaking study.”
The investigators have also developed a novel partnership with the American Heart Association’s Go Red For Women, a national movement to raise awareness of heart disease and to empower women to reduce their risk by learning about prevention. The investigators will also collaborate with various other organizations.
Karen N. Peart | EurekAlert!
The importance of biodiversity in forests could increase due to climate change
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02.10.2017 | International Institute for Applied Systems Analysis (IIASA)
The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.
Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
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