“This is the first study to focus on this high risk—and highly unstudied—group.” said Yale School of Public Health Associate Professor Judith Lichtman, co-principal investigator of the study. “There have been no large, prospective studies of this population, even though the death toll is comparable to that from breast cancer.”
She said the research team is exploring what accounts for premature heart disease in women and why they experience worse outcomes than men of similar age with heart disease.
The four-year grant will support the study of 2,000 women age 55 and younger with 1,000 men for comparison. The multi-site study bridges disciplines from basic biology and clinical sciences to psychology and health services research.
Although women under age 55 with heart attacks represent a small proportion of all patients with heart disease, they account for about 40,000 hospitalizations each year. About 8,000 women under the age of 55 die of heart disease annually, ranking it among the major causes of death in this group. While most women in this age group are protected from heart disease, notes Lichtman, prior research indicates that young women have a much greater risk of dying after a heart attack than men of the same age.
The study addresses questions ranging from genetics and clinical care to outcomes, including: How are outcomes of women different from those of men" What are the genetic, demographic, psychosocial, and behavioral factors that contribute to premature heart disease in women" How do delays in clinical presentation and treatment affect the risk and outcomes of women" Do women get the same quality of care as men"
“Despite the increasing focus on women with heart disease in recent years, we know little about heart disease in this population,” said principal investigator Harlan M. Krumholz, M.D., the Harold H. Hines, Jr. Professor of Medicine and Epidemiology and Public Health at Yale School of Medicine. “Since young women with heart disease are relatively rare at any one hospital, we have assembled an unprecedented network of almost 100 sites nationwide to identify and enroll women for this ground-breaking study.”
The investigators have also developed a novel partnership with the American Heart Association’s Go Red For Women, a national movement to raise awareness of heart disease and to empower women to reduce their risk by learning about prevention. The investigators will also collaborate with various other organizations.
Karen N. Peart | EurekAlert!
WAKE-UP provides new treatment option for stroke patients | International study led by UKE
17.05.2018 | Universitätsklinikum Hamburg-Eppendorf
First form of therapy for childhood dementia CLN2 developed
25.04.2018 | Universitätsklinikum Hamburg-Eppendorf
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
18.05.2018 | Power and Electrical Engineering
18.05.2018 | Information Technology
18.05.2018 | Information Technology