Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study indicates that greater efforts are needed to diagnose rectal cancer in young individuals who show potential signs of the disease.
Rectal cancer is considered to be rare among young individuals in the United States. Because underestimating rectal cancer's incidence may lead to missed or delayed diagnoses in younger people, Joshua Meyer, MD, a radiation oncologist currently at Fox Chase Cancer Center, led a team that analyzed trends in rectal cancer incidence in the United States compared with colon cancer trends. Dr. Meyer worked on this research while at the New York-Presbyterian Hospital/Weill Cornell Medical Center in New York City.
By conducting a retrospective study using data from the Surveillance Epidemiology and End Results (SEER) cancer registry, the investigators identified 7,661 colon and rectal cancer patients under age 40 years between 1973 and 2005. The researchers then calculated the change in incidence over time for colon and rectal cancers.
Overall rates of colon and of rectal cancer were low during the years of the study (1.11 cases and 0.42 cases per 100,000, respectively). While colon cancer rates remained essentially flat in individuals under age 40 years in recent decades, rectal cancer rates have been increasing since 1984. Specifically, between 1984 and 2005, the rate of rectal cancer diagnosis rose 3.8% per year.
"We suggest that in young people presenting with rectal bleeding or other common signs of rectal cancer, endoscopic evaluation should be considered in order to rule out a malignancy," said Dr. Meyer. "This is in contrast to what is frequently done, which is to attribute these findings to hemorrhoids. More frequent endoscopic evaluation may be able to decrease the documented delay in diagnosis among young people," he explained. Because the overall incidence of rectal cancer is relatively low, the authors do not advocate for a change in screening guidelines.
Article: "Increasing incidence of rectal cancer in patients under age 40: an analysis of the Surveillance, Epidemiology, and End Results database," Joshua E. Meyer, Tarun Narang, Felice H. Schnoll-Sussman, Mark B. Pochapin, Paul J. Christos, David L. Sherr. Cancer; Published Online: August 23, 2010 (DOI: 10.1002/cncr.25432).
David Sampson | EurekAlert!
Europe’s Demographic Future. Where the Regions Are Heading after a Decade of Crises
10.08.2017 | Berlin-Institut für Bevölkerung und Entwicklung
Scientists reveal source of human heartbeat in 3-D
07.08.2017 | University of Manchester
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
04.08.2017 | Event News
26.07.2017 | Event News
21.08.2017 | Life Sciences
21.08.2017 | Information Technology
18.08.2017 | Life Sciences