Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Rate of Follow-Up Surgeries After Partial Mastectomy Varies Greatly

01.02.2012
Findings could affect both cancer recurrence and overall survival rates

A new study reveals substantial differences – by both surgeon and institution – in the rates of follow-up surgeries for women who underwent a partial mastectomy for treatment of breast cancer.

Those differences, which cannot be explained by a patient’s medical or treatment history, could affect both cancer recurrence and overall survival rates, according to the study led by Laurence McCahill, M.D. of Van Andel Research Institute, Michigan State University’s College of Human Medicine, and the Richard J. Lacks Cancer Center.

The research appears in the Feb. 1 edition of the Journal of the American Medical Association.

“A partial mastectomy is one of the most commonly performed cancer operations in the United States,” said McCahill. “Currently, there are no readily identifiable quality measures that allow for meaningful comparisons of breast cancer surgical outcomes among surgeons and hospitals.

“But the current U.S. health care environment calls for increasing accountability for physicians and hospitals as well as transparency of treatment results.”

About three-fourths of women battling breast cancer have a partial mastectomy, and nearly one in four of them at some point have another surgery (re-excision) to remove additional tissue. A partial mastectomy intends to remove cancerous cells while maintaining maximum cosmetic appearance of the breast, but failure to remove all the cells at the initial operation requires additional surgery.

The additional operations can produce considerable psychological, physical and economic stress for patients and delay use of recommended supplemental therapies, according to the study, which measured variation in re-excision rates across hospitals and surgeons from 2003 to 2008. The study included more than 2,200 women with invasive breast cancer from four sites across the country.

The results show rates of re-excision varied widely and were not tied to any discernible characteristics for the patient. The study highlights the value of multicenter observational studies to pinpoint the variability in health care across different regions and health systems, McCahill said.

“While the long-term effect of this variability is beyond the scope of our study, it is feasible that cancer recurrence and overall survival could be affected by differences in initial surgical care,” he said. “The wide level of unexplained clinical variation itself represents a potential barrier to high-quality and cost-effective care of patients with breast cancer.”

The study was funded by a $1.1 million National Institutes of Health grant to Van Andel Research Institute via the American Recovery and Reinvestment Act of 2009. The two-year project led by Dr. McCahill was entitled "Improving Breast Cancer Surgery Quality through a Collaborative Surgery Database."

Media note: There will be multimedia content available, including the JAMA Report video, embedded and downloadable video, audio files, text, documents, and related links. This content will be available at 4 p.m. EST Jan. 31 at this link.

Michigan State University

Michigan State University has been working to advance the common good in uncommon ways for more than 150 years. One of the top research universities in the world, MSU focuses its vast resources on creating solutions to some of the world’s most pressing challenges, while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.

For MSU news on the Web, go to news.msu.edu. Follow MSU News on Twitter at twitter.com/MSUnews.

Contact: Jason Cody, University Relations: (517) 432-0924, cell (734) 755-0210, jason.cody@ur.msu.edu

Saint Mary’s Health Care

Saint Mary’s Health Care, a member of the new Mercy Health, is an integrated network of health care excellence offering a unique combination of capabilities to deliver a health care experience that is more complete and personally satisfying. Our commitment to offer the latest technology and most highly skilled physicians in a holistic, patient-centered environment has made us a progressive leader in cancer care, neuroscience, orthopedics, diabetes and endocrine care, kidney transplants, and integrative medicine.

The network encompasses more than 2,500 employees, a 336-bed, JCAHO-accredited teaching hospital, The Lacks Cancer Center, the area’s only dedicated cancer hospital, Saint Mary’s Southwest, The Wege Center for Health and Learning, the Diabetes and Endocrine Center, the Hauenstein Neuroscience Center housing the area’s most comprehensive neuroscience program and state-of-the-art Emergency and Trauma services, three fitness centers, five community outreach centers and affiliations with home health care, rehabilitation services, and the area's premier primary care network, Advantage Health Physician Network. Saint Mary’s is a member of Trinity Health, the country’s fourth-largest Catholic health care system.

To contact Laurence E. McCahill, M.D., call Micki Benz, Vice President, Communications, Saint Mary's Health Care, Grand Rapids MI. 616.685.1890 benzm@trinity-health.org

Van Andel Institute

Established by Jay and Betty Van Andel in 1996, Van Andel Institute (VAI) is an independent research and educational organization based in Grand Rapids, Mich., dedicated to preserving, enhancing and expanding the frontiers of medical science, and to achieving excellence in education by probing fundamental issues of education and the learning process. VARI, the research arm of VAI, is dedicated to probing the genetic, cellular and molecular origins of cancer, Parkinson and other diseases and working to translate those findings into effective therapies. This is accomplished through the work of over 200 researchers in 18 on-site laboratories and in collaborative partnerships that span the globe. VARI is affiliated with the Translational Genomics Research Institute, (TGen), of Phoenix, Arizona.

Joe Gavan | EurekAlert!
Further information:
http://www.vai.org

More articles from Studies and Analyses:

nachricht The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung

nachricht A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

New Study Will Help Find the Best Locations for Thermal Power Stations in Iceland

19.01.2017 | Earth Sciences

Not of Divided Mind

19.01.2017 | Life Sciences

Molecule flash mob

19.01.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>