Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Promising Alzheimer´s drug trialled in a large EU study

09.12.2013
An extensive European study is currently investigating whether a drug used to treat high blood pressure may also help patients with Alzheimer's disease.

The EU is investing almost 6 million euros on the project, in which Sahlgrenska Academy and Sahlgrenska University Hospital are responsible for Sweden's contribution.

The drug being trialled in the study, nilvadipine, is a well-proven treatment for high blood pressure. Research has shown that nilvadipine counters the formation of amyloid plaques in animal brains.

The drug is now to be trialled with 500 Alzheimer's patients in nine European countries.

... more about:
»Gothenburg »nerve cell

"Should this clinical trial be successful, nilvadipine would become the first Alzheimer's drug that not only reduces the symptoms of the disease but also acts on its causes. This could dramatically reduce Europe's costs for caring for patients with this neurodegenerative disease," says Anne Börjesson-Hanson, a researcher at Sahlgrenska Academy, University of Gothenburg, who is leading the Swedish participation in the study.

The patients in the study will be treated with nilvadipine or a placebo (inactive substance) for eighteen months. Patients who are already being treated with drugs to relieve the symptoms of Alzheimer's will continue to take them as before. Follow-up and check-ups will be carried out at the memory clinic at Sahlgrenska University Hospital.

"We will carry out repeated tests on the patients to see whether there are changes in memory and cognition during the trial period," says Anne Börjesson-Hanson.

This major European research collaboration is called NILVAD, and is being coordinated from Trinity College in Dublin, Ireland. Research teams in the UK, France, Netherlands, Greece, Hungary, Italy and Germany are taking part alongside Ireland and Sweden.

For further information about the project, see:
www.nilvad.eu
ABOUT ALZHEIMER'S DISEASE
Alzheimer's is one of the major widespread diseases. Over 100 000 people are affected in Sweden alone. Europe's ageing population means twice as many people are expected to be affected by 2050. The disease is caused by pathological changes in nerve cells in the brain, affecting memory in particular. The disease often leads to premature death. Alzheimer's causes not only great distress to patients and relatives, but also enormous costs to society.
Contact:
Anne Börjesson-Hanson, lead researcher at Sahlgrenska Academy at the University of Gothenburg, Sweden
+46 31 343 86 69
+46 76 77 66 562
anne.borjesson@neuro.gu.se

Torsten Arpi | idw
Further information:
http://www.gu.se
http://www.sahlgrenska.gu.se/english/news_and_events/news/News_Detail/promising-alzheimer-s-drug-trialled-in-a-large-eu-study.cid119012

Further reports about: Gothenburg nerve cell

More articles from Studies and Analyses:

nachricht Drone vs. truck deliveries: Which create less carbon pollution?
31.05.2017 | University of Washington

nachricht New study: How does Europe become a leading player for software and IT services?
03.04.2017 | Fraunhofer-Institut für System- und Innovationsforschung (ISI)

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Quantum thermometer or optical refrigerator?

23.06.2017 | Physics and Astronomy

A 100-year-old physics problem has been solved at EPFL

23.06.2017 | Physics and Astronomy

Equipping form with function

23.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>