The EU is investing almost 6 million euros on the project, in which Sahlgrenska Academy and Sahlgrenska University Hospital are responsible for Sweden's contribution.
The drug being trialled in the study, nilvadipine, is a well-proven treatment for high blood pressure. Research has shown that nilvadipine counters the formation of amyloid plaques in animal brains.
The drug is now to be trialled with 500 Alzheimer's patients in nine European countries.
"Should this clinical trial be successful, nilvadipine would become the first Alzheimer's drug that not only reduces the symptoms of the disease but also acts on its causes. This could dramatically reduce Europe's costs for caring for patients with this neurodegenerative disease," says Anne Börjesson-Hanson, a researcher at Sahlgrenska Academy, University of Gothenburg, who is leading the Swedish participation in the study.
The patients in the study will be treated with nilvadipine or a placebo (inactive substance) for eighteen months. Patients who are already being treated with drugs to relieve the symptoms of Alzheimer's will continue to take them as before. Follow-up and check-ups will be carried out at the memory clinic at Sahlgrenska University Hospital.
"We will carry out repeated tests on the patients to see whether there are changes in memory and cognition during the trial period," says Anne Börjesson-Hanson.
This major European research collaboration is called NILVAD, and is being coordinated from Trinity College in Dublin, Ireland. Research teams in the UK, France, Netherlands, Greece, Hungary, Italy and Germany are taking part alongside Ireland and Sweden.For further information about the project, see:
Torsten Arpi | idw
The Great Unknown: Risk-Taking Behavior in Adolescents
19.01.2017 | Max-Planck-Institut für Bildungsforschung
A sudden drop in outdoor temperature increases the risk of respiratory infections
11.01.2017 | University of Gothenburg
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Health and Medicine
23.01.2017 | Physics and Astronomy
23.01.2017 | Process Engineering