The study was performed at the University of Washington and Seattle Cancer Care Alliance in Seattle, WA.
The review initiated with 592 patients who were recently diagnosed with breast cancer and underwent staging with preoperative breast MRI. The analysis set was comprised of 570 patients, whose biopsy rates, positive predictive values (PPVs) of biopsy, and overall cancer yields were calculated and compared using the chi-square test across patient age, breast density, index tumor type, receptor status and lymph node status.
"Our data add to the growing body of literature that documents breast MRI's ability to detect otherwise occult additional disease in patients who have been newly diagnosed with breast cancer," said Robert Gutierrez, MD, lead author of the study.
"We found that use of preoperative breast MRI in newly diagnosed cancer patients resulted in an added cancer yield of 12%.This is much higher than the added cancer yield of .08 to 6.7% seen with high risk screening breast MRI, a more widely accepted indication for breast MRI, " said Gutierrez.
"A major strength of our study is our sample size of 570 patients, which is larger than most prior investigations. Additionally, unlike the majority of preoperative breast MRI studies, our patient population is more representative of a broad diagnostic population, which is a result of the practice pattern at our site of routinely performing preoperative breast MRI in newly diagnosed breast cancer patients, "he said.
This study appears in the January 2011 issue of the American Journal of Roentgenology.
Keri Sperry | EurekAlert!
Diagnoses: When Are Several Opinions Better Than One?
19.07.2016 | Max-Planck-Institut für Bildungsforschung
High in calories and low in nutrients when adolescents share pictures of food online
07.04.2016 | University of Gothenburg
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences