Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Prenatal Exposure to BPA Might Explain Aggressive Behavior in Some 2-Year-old Girls

07.10.2009
Daughters of women exposed to a common chemical found in some plastics while they were pregnant are more likely to have unusually aggressive and hyperactive behaviors as 2-year-olds, according to a new study by researchers at Simon Fraser University, the University of North Carolina at Chapel Hill and Cincinnati Children’s Hospital.

The study, published Oct. 6, 2009 in the journal Environmental Health Perspectives, is the first to examine if there is a link between prenatal bisphenol A (BPA) exposure and behavior problems in children. Results suggest that if a woman is exposed to BPA early in her pregnancy, development of the baby’s nervous system might be adversely affected.

BPA is commonly used in the production of polycarbonate plastics and epoxy resins that can be found, for example, in some types of plastic bottles, canned food linings, water supply pipes and medical tubing. About 93 percent of people in the United States have detectible levels of BPA in their urine, according to the Centers for Disease Control and Prevention.

Researchers found that daughters of women who had higher concentrations of BPA in their urine samples during pregnancy were more likely to have aggressive and hyperactive behaviors than children of women with lower BPA levels, especially if higher exposure was seen earlier in pregnancy.

“In other words, girls whose mothers had higher BPA exposure were more likely to act like boys than girls whose mothers had lower BPA levels, especially if the exposure was seen earlier in pregnancy,” said the study’s lead author Joe Braun, a doctoral student in epidemiology at the UNC Gillings School of Global Public Health. “Boys’ behavior did not seem to be affected, although there was some evidence of increased internalizing scores among BPA-exposed boys.”

Researchers do not know why girls seem to be affected by the exposure more or differently than boys.

BPA has been used in products for decades, and concerns about its safety have been growing in recent years, Braun said. Previous studies in mice have shown that the offspring of mothers with high BPA exposure during pregnancy were more aggressive than offspring not exposed to high prenatal levels of BPA.

“We wanted to know if there was a risk in humans for neurodevelopment problems,” he said. “Study results indicate that exposure to BPA early in the pregnancy seems to be the most critical issue. The most damaging exposure might happen before a woman even knows she’s pregnant.”

Braun worked with researchers at the Cincinnati Children’s Hospital Medical Center, the University of Cincinnati, the Centers for Disease Control and Prevention, and Simon Fraser University in Vancouver, British Columbia.

For the study, urine samples were taken from 249 pregnant women in Cincinnati, Ohio, at 16 weeks and 26 weeks of pregnancy, and again at birth. BPA concentrations in the samples were measured. Then, when the children were 2 years old, behavior problems were assessed, using the Behavioral Assessment System for Children-2 (BASC-2).

“Many government agencies and consumers in the U.S., Canada and around the world have expressed concerns about BPA exposure, especially in children,” said Dr. Bruce Lanphear, professor of children’s environmental health in the Faculty of Health Sciences at Simon Fraser University and the study’s senior author. “Canada has banned BPA in baby bottles and other baby products, but that might not be sufficient to protect children. Although this is the first study of its kind, it suggests that we may also need to reduce exposures during pregnancy.”

The study was funded in part by the National Institute of Environmental Health Sciences and the U.S. Environmental Protection Agency.

For more information on the study, visit: www.ehponline.org.

Note: Braun can be reached at (919) 951-8519 or jmbraun@unc.edu. Lanphear can be reached at (778) 387-3939 or blanphear@sfu.ca.

Ramona DuBose | Newswise Science News
Further information:
http://www.unc.edu

More articles from Studies and Analyses:

nachricht Multi-year study finds 'hotspots' of ammonia over world's major agricultural areas
17.03.2017 | University of Maryland

nachricht Diabetes Drug May Improve Bone Fat-induced Defects of Fracture Healing
17.03.2017 | Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke

All articles from Studies and Analyses >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Northern oceans pumped CO2 into the atmosphere

27.03.2017 | Earth Sciences

Fingerprint' technique spots frog populations at risk from pollution

27.03.2017 | Life Sciences

Big data approach to predict protein structure

27.03.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>